Neuroprotective mechanisms of rutin for spinal cord injury through anti-oxidation and anti-inflammation and inhibition of p38 mitogen activated protein kinase pathway

Neuroprotective mechanisms of rutin for spinal cord injury through anti-oxidation and anti-inflammation and inhibition of p38 mitogen activated protein kinase pathway

Rutin has anti-inflammatory, antioxidant, anti-viral, anti-tumor and immune regulatory effects. However, the neuroprotective effects of rutin in spinal cord injury are unknown. The p38 mitogen activated protein kinase (p38 MAPK) pathway is the most important member of the MAPK family that controls i...

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Bibliographic Details
Main Authors: Hong-liang Song, Xiang Zhang, Wen-zhao Wang, Rong-han Liu, Kai Zhao, Ming-yuan Liu, Wei-ming Gong, Bin Ning
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; spinal cord injury; rutin; oxidative stress; antioxidant; anti-inflammation; p38 mitogen activated protein kinase pathway; anti-apoptosis; caspase-3; caspase-9; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=1;spage=128;epage=134;aulast=Song

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