Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma
Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between the patients diagnosed as low-risk or intermedia...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-03-01
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| Series: | Bagcilar Medical Bulletin |
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| Online Access: |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-preoperative-hematological-parameter/58573
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| author | Serkan Kumbasar Dilruba Karaca Fatma Ketenci Gencer Özlem Khatip Hatice Yaşat Nacar Nazime Binnur Cömert Esra Nazlı Döktür |
| author_facet | Serkan Kumbasar Dilruba Karaca Fatma Ketenci Gencer Özlem Khatip Hatice Yaşat Nacar Nazime Binnur Cömert Esra Nazlı Döktür |
| author_sort | Serkan Kumbasar |
| collection | DOAJ |
| description | Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between the patients diagnosed as low-risk or intermediate-advanced risk endometrial cancer and those with benign endometrial pathology.Method:The study included patients who underwent hysteroscopy, dilatation curettage, or endometrial biopsy with endometrial sampling due to abnormal uterine bleeding between March 2014 and April 2022. The groups were formed according to the pathology report of endometrial sampling. In addition, subgroup analysis was made based on intraoperative frozen evaluation and final pathology results. Group 1 included benign endometrial pathology; group 2 included lowrisk endometrial adeno cancer cases; and group 3 were those with endometrial adeno cancer other than low-risk endometrial cancer.Results:No statistically significant difference was found between the groups in terms of neutrophil count, lymphocyte count, platelet count, eosinophil count, MPV, PDW, NLR, MLR, ELR, PLR (p>0.05). Endometrial thickness, body mass index, advanced age were found to be statistically significant in the endometrial adeno cancer groups.Conclusion:MPV, NLR, ELR, MLR, and PLR values did not show any difference between groups may be because systemic inflammation was not triggered in low-risk or medium-high-risk endometrial cancer. |
| first_indexed | 2024-04-10T04:06:21Z |
| format | Article |
| id | doaj.art-e373fc7610b546c3b37db1c683f07cc6 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-10T04:06:21Z |
| publishDate | 2023-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-e373fc7610b546c3b37db1c683f07cc62023-03-13T06:16:09ZengGalenos YayineviBagcilar Medical Bulletin2547-94312023-03-018161210.4274/BMB.galenos.2022.2022-10-08813049054Evaluation of Preoperative Hematological Parameters in Patients with Endometrial AdenocarcinomaSerkan Kumbasar0Dilruba Karaca1Fatma Ketenci Gencer2Özlem Khatip3Hatice Yaşat Nacar4Nazime Binnur Cömert5Esra Nazlı Döktür6 University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between the patients diagnosed as low-risk or intermediate-advanced risk endometrial cancer and those with benign endometrial pathology.Method:The study included patients who underwent hysteroscopy, dilatation curettage, or endometrial biopsy with endometrial sampling due to abnormal uterine bleeding between March 2014 and April 2022. The groups were formed according to the pathology report of endometrial sampling. In addition, subgroup analysis was made based on intraoperative frozen evaluation and final pathology results. Group 1 included benign endometrial pathology; group 2 included lowrisk endometrial adeno cancer cases; and group 3 were those with endometrial adeno cancer other than low-risk endometrial cancer.Results:No statistically significant difference was found between the groups in terms of neutrophil count, lymphocyte count, platelet count, eosinophil count, MPV, PDW, NLR, MLR, ELR, PLR (p>0.05). Endometrial thickness, body mass index, advanced age were found to be statistically significant in the endometrial adeno cancer groups.Conclusion:MPV, NLR, ELR, MLR, and PLR values did not show any difference between groups may be because systemic inflammation was not triggered in low-risk or medium-high-risk endometrial cancer. http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-preoperative-hematological-parameter/58573 elrendometrium adeno camlrmpvnlrplr |
| spellingShingle | Serkan Kumbasar Dilruba Karaca Fatma Ketenci Gencer Özlem Khatip Hatice Yaşat Nacar Nazime Binnur Cömert Esra Nazlı Döktür Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma Bagcilar Medical Bulletin elr endometrium adeno ca mlr mpv nlr plr |
| title | Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma |
| title_full | Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma |
| title_fullStr | Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma |
| title_full_unstemmed | Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma |
| title_short | Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma |
| title_sort | evaluation of preoperative hematological parameters in patients with endometrial adenocarcinoma |
| topic | elr endometrium adeno ca mlr mpv nlr plr |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-preoperative-hematological-parameter/58573
|
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