Electron transfer-triggered imaging of EGFR signaling activity

Here, the authors design a nanoprobe for in vivo imaging of electronic transfer, consisting of a ferrocene-DNA polymer to transfer electrons to luminescent nanoparticles, changing their optical signal. Using this probe, they map activation of EGFR signalling during tumour treatment.

Bibliographic Details
Main Authors: Jie Tan, Hao Li, Cailing Ji, Lei Zhang, Chenxuan Zhao, Liming Tang, Caixin Zhang, Zhijun Sun, Weihong Tan, Quan Yuan
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28213-y