Identifying the genetic determinants of transcription factor activity
Analysis of parallel genotyping and expression profiling data has shown that mRNA expression levels are highly heritable. Currently, only a tiny fraction of this genetic variance can be mechanistically accounted for. The influence of trans‐acting polymorphisms on gene expression traits is often medi...
Main Authors: | Eunjee Lee, Harmen J Bussemaker |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.64 |
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