Identifying the genetic determinants of transcription factor activity

Analysis of parallel genotyping and expression profiling data has shown that mRNA expression levels are highly heritable. Currently, only a tiny fraction of this genetic variance can be mechanistically accounted for. The influence of trans‐acting polymorphisms on gene expression traits is often medi...

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Bibliographic Details
Main Authors: Eunjee Lee, Harmen J Bussemaker
Format: Article
Language:English
Published: Springer Nature 2010-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2010.64

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