An in vivo test to assess mefloquine 25 mg/kg for the treatment of uncomplicated falciparum malaria in Rondônia, Brazil

An in vivo test to assess mefloquine 25 mg/kg for the treatment of uncomplicated falciparum malaria in Rondônia, Brazil

Drug-resistant Plasmodium falciparum is undermining malaria control efforts worldwide. In Brazil, mefloquine (MQ) at a dose of 15 mg/kg body weight is used to treat P. falciparum. At this dose, MQ resistance developed rapidly in Thailand. Use of a higher MQ dose may retard the development of resista...

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Bibliographic Details
Main Authors: S.A. Basano, A. Bianco, W.R..J Taylor, P. Olliaro, L.M.A. Camargo
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Malaria
mefloquine
Amazon
Rondônia
therapeutics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400013&lng=en&tlng=en

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