Flank Pain as a First Symptom of a Diffuse Midline Glioma

Diffuse midline gliomas are a new entity in the WHO Classification of Tumors of the Central Nervous System, corresponding to grade 4 gliomas. The diagnostic pathognomonic feature is the presence of a H3K27M mutation. Although mainly seen in children, cases in adults have also been reported. The symp...

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Bibliographic Details
Main Authors: Burc Bassa, Achim Battmann, Eva Maria Craemer, Uta Meyding-Lamadé
Format: Article
Language:English
Published: Karger Publishers 2023-01-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/528311
Description
Summary:Diffuse midline gliomas are a new entity in the WHO Classification of Tumors of the Central Nervous System, corresponding to grade 4 gliomas. The diagnostic pathognomonic feature is the presence of a H3K27M mutation. Although mainly seen in children, cases in adults have also been reported. The symptoms are highly variable and usually dependent on the location and extent of spinal cord compression.
ISSN:1662-680X