Pre-treatment with IL2 gene therapy alleviates Staphylococcus aureus arthritis in mice

Pre-treatment with IL2 gene therapy alleviates Staphylococcus aureus arthritis in mice

Abstract Background Staphylococcus aureus (S. aureus) arthritis is one of the most detrimental joint diseases known and leads to severe joint destruction within days. We hypothesized that the provision of auxiliary immunoregulation via an expanded compartment of T regulatory cells (Tregs) could damp...

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Bibliographic Details
Main Authors: Berglind Bergmann, Ying Fei, Pernilla Jirholt, Zhicheng Hu, Maria Bergquist, Abukar Ali, Catharina Lindholm, Olov Ekwall, Guillaume Churlaud, David Klatzmann, Tao Jin, Inger Gjertsson
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Infectious Diseases
Subjects:
T regulatory cells
Tregs
IL2
S. aureus
Arthritis
Mice
Online Access:http://link.springer.com/article/10.1186/s12879-020-4880-8

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