The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya
Mammary gland tumours are frequently reported in adult female mice. It broadly affects the productivity and breeding performance of mice in breeding centres. The tumours might occur spontaneously due to internal factors such as genetic mutation and hormonal disturbance, however, external causes such...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga, Faculty of Veterinary Medicine
2022-04-01
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| Series: | Jurnal Medik Veteriner |
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| Online Access: | https://e-journal.unair.ac.id/JMV/article/view/32606 |
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| author | Maulidi Robingi Mardiyani Wukirani Essly Hervianingsih Adha Sang Ayu Putri Aristya Dewi Ani Setianingrum Dyah Ayu Oktavianie Ardhiana Pratama Andreas Bandang Hardian |
| author_facet | Maulidi Robingi Mardiyani Wukirani Essly Hervianingsih Adha Sang Ayu Putri Aristya Dewi Ani Setianingrum Dyah Ayu Oktavianie Ardhiana Pratama Andreas Bandang Hardian |
| author_sort | Maulidi Robingi Mardiyani Wukirani |
| collection | DOAJ |
| description | Mammary gland tumours are frequently reported in adult female mice. It broadly affects the productivity and breeding performance of mice in breeding centres. The tumours might occur spontaneously due to internal factors such as genetic mutation and hormonal disturbance, however, external causes such as Mouse Mammary Tumour Virus (MMTV) infection was also reported. This study aimed to prove that age and number of parturition associate with mammary gland tumour case rate in female mice in Malang Raya. Chi-square tests were employed to analyse the association between risk factors and mammary gland tumour case rate in this study. Histopathologic analysis described three subtypes of mammary gland tumours in mice which were adenoma, adenocarcinoma type A and adenocarcinoma type B. Chi-square tests results of tumour case rate toward age and number of parturitions were consecutively 0,004 and 0,0025 which indicated that age and number of parturitions were associated with mammary gland tumours case rate in mice in Malang Raya. The mapping of tumour case distribution visually showed a trend that higher disease proportions were spotted in higher altitude of sampling location. This might relate to the geographical breeding characteristics or temperature which needs further study to explore the association of spatial factors with the mammary tumour incidence in mice. |
| first_indexed | 2024-04-11T14:03:07Z |
| format | Article |
| id | doaj.art-e38299ab6e8249c8a90136171ddbe395 |
| institution | Directory Open Access Journal |
| issn | 2615-7497 2581-012X |
| language | English |
| last_indexed | 2024-04-11T14:03:07Z |
| publishDate | 2022-04-01 |
| publisher | Universitas Airlangga, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Jurnal Medik Veteriner |
| spelling | doaj.art-e38299ab6e8249c8a90136171ddbe3952022-12-22T04:20:01ZengUniversitas Airlangga, Faculty of Veterinary MedicineJurnal Medik Veteriner2615-74972581-012X2022-04-015191510.20473/jmv.vol5.iss1.2022.9-1526737The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang RayaMaulidi Robingi Mardiyani Wukirani0Essly Hervianingsih Adha1Sang Ayu Putri Aristya Dewi2Ani Setianingrum3https://orcid.org/0000-0003-1465-3961Dyah Ayu Oktavianie Ardhiana Pratama4Andreas Bandang Hardian5https://orcid.org/0000-0002-2705-2412Mahasiswa Program Pendidikan Dokter Hewan, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Mahasiswa Program Pendidikan Dokter Hewan, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Mahasiswa Program Pendidikan Dokter Hewan, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Laboratorium Kesehatan Masyarakat Veteriner, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Laboratorium Patologi Anatomi Veteriner, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Laboratorium Patologi Anatomi Veteriner, Fakultas Kedokteran Hewan, Universitas Brawijaya, Puncak Dieng Eksklusif, Kalisongo, Dau, Malang 65151Mammary gland tumours are frequently reported in adult female mice. It broadly affects the productivity and breeding performance of mice in breeding centres. The tumours might occur spontaneously due to internal factors such as genetic mutation and hormonal disturbance, however, external causes such as Mouse Mammary Tumour Virus (MMTV) infection was also reported. This study aimed to prove that age and number of parturition associate with mammary gland tumour case rate in female mice in Malang Raya. Chi-square tests were employed to analyse the association between risk factors and mammary gland tumour case rate in this study. Histopathologic analysis described three subtypes of mammary gland tumours in mice which were adenoma, adenocarcinoma type A and adenocarcinoma type B. Chi-square tests results of tumour case rate toward age and number of parturitions were consecutively 0,004 and 0,0025 which indicated that age and number of parturitions were associated with mammary gland tumours case rate in mice in Malang Raya. The mapping of tumour case distribution visually showed a trend that higher disease proportions were spotted in higher altitude of sampling location. This might relate to the geographical breeding characteristics or temperature which needs further study to explore the association of spatial factors with the mammary tumour incidence in mice.https://e-journal.unair.ac.id/JMV/article/view/32606mammary gland tumourageparturitionmicebreeding |
| spellingShingle | Maulidi Robingi Mardiyani Wukirani Essly Hervianingsih Adha Sang Ayu Putri Aristya Dewi Ani Setianingrum Dyah Ayu Oktavianie Ardhiana Pratama Andreas Bandang Hardian The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya Jurnal Medik Veteriner mammary gland tumour age parturition mice breeding |
| title | The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya |
| title_full | The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya |
| title_fullStr | The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya |
| title_full_unstemmed | The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya |
| title_short | The Association of Age and Number of Parturition with Mammary Gland Tumor Case Rate in Mice in Malang Raya |
| title_sort | association of age and number of parturition with mammary gland tumor case rate in mice in malang raya |
| topic | mammary gland tumour age parturition mice breeding |
| url | https://e-journal.unair.ac.id/JMV/article/view/32606 |
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