The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators
Introduction: Physical activity and exercise due to increased cellular oxidative process lead to increased free-radical production and reactive oxygen species. "Oxidative stress" is defined as the disturbed balance between oxidative and antioxidative indicators in favor of oxidative specie...
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| Format: | Article |
| Language: | English |
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Zabol University of Medical sciences
2017-03-01
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| Series: | International Journal of Basic Science in Medicine |
| Subjects: | |
| Online Access: | http://ijbsm.zbmu.ac.ir/PDF/IJBSM-2-29.pdf |
| _version_ | 1818759759466070016 |
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| author | Reza Delavar Mehdi Mogharnasi Nazanin Khoobkhahi |
| author_facet | Reza Delavar Mehdi Mogharnasi Nazanin Khoobkhahi |
| author_sort | Reza Delavar |
| collection | DOAJ |
| description | Introduction: Physical activity and exercise due to increased cellular oxidative process lead to increased free-radical production and reactive oxygen species. "Oxidative stress" is defined as the disturbed balance between oxidative and antioxidative indicators in favor of oxidative species. Methods: In this semi-experimental study, 23 sedentary boys volunteered to participate. They were randomly assigned to 2 groups of training (n = 13) and control (n = 10). The combined trainings included endurance running with 60% to 80% of maximum heart rate and resistance weight training with 40% to 50% and one repetition maximum intensity. Blood samples were taken from the subjects’ forearm vein, 24 hours before and 48 hours after the last training session in a fasting state. Paired and independent t tests were used to locate the inner-group and inter-group changes respectively. Data were analyzed using SPSS version 20. A P <0.01 was considered significant. Results: Malondialdehyde (MDA) level as a marker of oxidative stress in the exercise group decreased significantly after 24 sessions of exercise (P = 0.015), while the index of total antioxidant capacity (TAC) significantly increased in the exercise group (P = 0.021). There was no significant difference in the 2 indexes in the control group (P < 0.05). Conclusion: The present study suggests that combined training provides a good balance between indicators of oxidative stress and antioxidant defense among sedentary boys and this would prevent the overproduction of free radicals. |
| first_indexed | 2024-12-18T06:47:50Z |
| format | Article |
| id | doaj.art-e3829f5f12024adc8b33cfeedba00141 |
| institution | Directory Open Access Journal |
| issn | 2476-664X |
| language | English |
| last_indexed | 2024-12-18T06:47:50Z |
| publishDate | 2017-03-01 |
| publisher | Zabol University of Medical sciences |
| record_format | Article |
| series | International Journal of Basic Science in Medicine |
| spelling | doaj.art-e3829f5f12024adc8b33cfeedba001412022-12-21T21:17:26ZengZabol University of Medical sciencesInternational Journal of Basic Science in Medicine2476-664X2017-03-0121293210.15171/ijbsm.2017.07IJBSM-2105-20170131225814The Effects of Combined Training on OxidativeStress and Antioxidant Defense IndicatorsReza Delavar0Mehdi Mogharnasi1Nazanin Khoobkhahi2Assistant Professor, Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, IranAssociate Professor, Department of Sports Physiology, Faculty of Sport Sciences, University of Birjand, Birjand, IranMSc Student, Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, IranIntroduction: Physical activity and exercise due to increased cellular oxidative process lead to increased free-radical production and reactive oxygen species. "Oxidative stress" is defined as the disturbed balance between oxidative and antioxidative indicators in favor of oxidative species. Methods: In this semi-experimental study, 23 sedentary boys volunteered to participate. They were randomly assigned to 2 groups of training (n = 13) and control (n = 10). The combined trainings included endurance running with 60% to 80% of maximum heart rate and resistance weight training with 40% to 50% and one repetition maximum intensity. Blood samples were taken from the subjects’ forearm vein, 24 hours before and 48 hours after the last training session in a fasting state. Paired and independent t tests were used to locate the inner-group and inter-group changes respectively. Data were analyzed using SPSS version 20. A P <0.01 was considered significant. Results: Malondialdehyde (MDA) level as a marker of oxidative stress in the exercise group decreased significantly after 24 sessions of exercise (P = 0.015), while the index of total antioxidant capacity (TAC) significantly increased in the exercise group (P = 0.021). There was no significant difference in the 2 indexes in the control group (P < 0.05). Conclusion: The present study suggests that combined training provides a good balance between indicators of oxidative stress and antioxidant defense among sedentary boys and this would prevent the overproduction of free radicals.http://ijbsm.zbmu.ac.ir/PDF/IJBSM-2-29.pdfCombined trainingOxidative stress markersAntioxidant defense |
| spellingShingle | Reza Delavar Mehdi Mogharnasi Nazanin Khoobkhahi The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators International Journal of Basic Science in Medicine Combined training Oxidative stress markers Antioxidant defense |
| title | The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators |
| title_full | The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators |
| title_fullStr | The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators |
| title_full_unstemmed | The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators |
| title_short | The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators |
| title_sort | effects of combined training on oxidativestress and antioxidant defense indicators |
| topic | Combined training Oxidative stress markers Antioxidant defense |
| url | http://ijbsm.zbmu.ac.ir/PDF/IJBSM-2-29.pdf |
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