Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study
Abstract Background Obesity is well known as a risk factor for cardiovascular disease. We aimed to determine the performance of and the optimal cutoff values for obesity indices to discriminate the presence of metabolic abnormalities as a primary risk factor for cardiovascular diseases in a Health E...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-021-10490-9 |
| _version_ | 1818912417948631040 |
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| author | Sooyoung Cho Aesun Shin Ji-Yeob Choi Sang Min Park Daehee Kang Jong-Koo Lee |
| author_facet | Sooyoung Cho Aesun Shin Ji-Yeob Choi Sang Min Park Daehee Kang Jong-Koo Lee |
| author_sort | Sooyoung Cho |
| collection | DOAJ |
| description | Abstract Background Obesity is well known as a risk factor for cardiovascular disease. We aimed to determine the performance of and the optimal cutoff values for obesity indices to discriminate the presence of metabolic abnormalities as a primary risk factor for cardiovascular diseases in a Health Examinees study (HEXA). Methods The current study analyzed 134,195 participants with complete anthropometric and laboratory information in a Health Examinees study, consisting of the Korean population aged 40 to 69 years. The presence of metabolic abnormality was defined as having at least one of the following: hypertension, hyperglycemia, or dyslipidemia. The area under the receiver operating characteristic curve (AUC) and 95% confidence intervals (CIs) were calculated for body mass index, waist to hip ratio, waist to height ratio, waist circumference, and conicity index. Results The AUC of metabolic abnormalities was the highest for waist-to-height ratio (AUC [95% CIs], 0.677 [0.672–0.683] among men; 0.691 [0.687–0.694] among women), and the lowest for the C index (0.616 [0.611–0.622] among men; 0.645 [0.641–0.649] among women) among both men and women. The optimal cutoff values were 24.3 kg/m2 for the body mass index, 0.887 for the waist-to-hip ratio, 0.499 for the waist-to-height ratio, 84.4 cm for waist circumference and 1.20 m3/2/kg1/2 for the conicity index among men, and 23.4 kg/m2 for the body mass index, 0.832 for the waist-to-hip ratio, 0.496 for the waist-to-height ratio, 77.0 cm for the waist circumference and 1.18 m3/2/kg1/2 for the conicity index among women. Conclusion The waist-to-height ratio is the best index to discriminate metabolic abnormalities among middle-aged Koreans. The optimal cutoff of obesity indices is lower than the international guidelines for obesity. It would be appropriate to use the indices for abdominal obesity rather than general obesity and to consider a lower level of body mass index and waist circumference than the current guidelines to determine obesity-related health problems in Koreans. |
| first_indexed | 2024-12-19T23:14:16Z |
| format | Article |
| id | doaj.art-e383c631290942339fdb2af0a8b731c1 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-19T23:14:16Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-e383c631290942339fdb2af0a8b731c12022-12-21T20:02:08ZengBMCBMC Public Health1471-24582021-03-012111810.1186/s12889-021-10490-9Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees studySooyoung Cho0Aesun Shin1Ji-Yeob Choi2Sang Min Park3Daehee Kang4Jong-Koo Lee5Department of Preventive Medicine, Seoul National University College of MedicineDepartment of Preventive Medicine, Seoul National University College of MedicineCancer Research Institute, Seoul National UniversityDepartment of Biomedical Science, Seoul National University Graduate SchoolDepartment of Preventive Medicine, Seoul National University College of MedicineDepartment of Family Medicine, Seoul National University College of MedicineAbstract Background Obesity is well known as a risk factor for cardiovascular disease. We aimed to determine the performance of and the optimal cutoff values for obesity indices to discriminate the presence of metabolic abnormalities as a primary risk factor for cardiovascular diseases in a Health Examinees study (HEXA). Methods The current study analyzed 134,195 participants with complete anthropometric and laboratory information in a Health Examinees study, consisting of the Korean population aged 40 to 69 years. The presence of metabolic abnormality was defined as having at least one of the following: hypertension, hyperglycemia, or dyslipidemia. The area under the receiver operating characteristic curve (AUC) and 95% confidence intervals (CIs) were calculated for body mass index, waist to hip ratio, waist to height ratio, waist circumference, and conicity index. Results The AUC of metabolic abnormalities was the highest for waist-to-height ratio (AUC [95% CIs], 0.677 [0.672–0.683] among men; 0.691 [0.687–0.694] among women), and the lowest for the C index (0.616 [0.611–0.622] among men; 0.645 [0.641–0.649] among women) among both men and women. The optimal cutoff values were 24.3 kg/m2 for the body mass index, 0.887 for the waist-to-hip ratio, 0.499 for the waist-to-height ratio, 84.4 cm for waist circumference and 1.20 m3/2/kg1/2 for the conicity index among men, and 23.4 kg/m2 for the body mass index, 0.832 for the waist-to-hip ratio, 0.496 for the waist-to-height ratio, 77.0 cm for the waist circumference and 1.18 m3/2/kg1/2 for the conicity index among women. Conclusion The waist-to-height ratio is the best index to discriminate metabolic abnormalities among middle-aged Koreans. The optimal cutoff of obesity indices is lower than the international guidelines for obesity. It would be appropriate to use the indices for abdominal obesity rather than general obesity and to consider a lower level of body mass index and waist circumference than the current guidelines to determine obesity-related health problems in Koreans.https://doi.org/10.1186/s12889-021-10490-9Obesity; hypertensionHyperglycemiaDyslipidemiaSensitivity and specificityArea under the curve |
| spellingShingle | Sooyoung Cho Aesun Shin Ji-Yeob Choi Sang Min Park Daehee Kang Jong-Koo Lee Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study BMC Public Health Obesity; hypertension Hyperglycemia Dyslipidemia Sensitivity and specificity Area under the curve |
| title | Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study |
| title_full | Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study |
| title_fullStr | Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study |
| title_full_unstemmed | Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study |
| title_short | Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study |
| title_sort | optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in korea results from a health examinees study |
| topic | Obesity; hypertension Hyperglycemia Dyslipidemia Sensitivity and specificity Area under the curve |
| url | https://doi.org/10.1186/s12889-021-10490-9 |
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