Whole transcriptome sequencing reveals a TCF4-ZNF384 fusion in acute lymphoblastic leukemia

Whole transcriptome sequencing reveals a TCF4-ZNF384 fusion in acute lymphoblastic leukemia

Previous studies have shown that, the clinical features and prognosis of ZNF384-rearranged pediatric acute lymphoblastic leukemia (ALL) depend on its translocation partners. We report two cases of TCF4-ZNF384 fusion, one 6-year-old girl and one 10-year-old boy, both diagnosed by whole-transcriptome...

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Bibliographic Details
Main Authors: Zhengyu Wu, Fang Zhang, Chengzhu Liu, Shuhong Shen, Jinhua Chu, Linhai Yang, Zhiwei Xie, Yu Liu, Kangkang Liu, Ningling Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
acute lymphoblastic leukemia
ZNF384
RNA sequencing
TCF4
pediatic
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.900054/full

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