Alpha-gal syndrome – A case report of tick-borne anaphylactic shock
The most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome. We present a case of a protracted life-threatenin...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2023-06-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/3939 |
| _version_ | 1797782653204692992 |
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| author | Jiri Muller Jaroslav Radej Miroslav Kriz Eliska Hunkova Jan Kasparek Martin Matejovic |
| author_facet | Jiri Muller Jaroslav Radej Miroslav Kriz Eliska Hunkova Jan Kasparek Martin Matejovic |
| author_sort | Jiri Muller |
| collection | DOAJ |
| description | The most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome. We present a case of a protracted life-threatening manifestation of alpha-gal syndrome, which, due to an unusual absence of typical features of anaphylaxis can masquerade as septic shock and calls attention to the premature diagnostic closure as a contributor to diagnostic error. Alpha-gal syndrome is a relatively new, but increasingly recognised health issue. We propose that alpha-gal syndrome should be considered in the differential diagnosis of vasoplegic shock of unclear aetiology even in the absence of typical allergic symptomatology and typical allergen exposure since alpha-gal is present in a wide variety of carriers. |
| first_indexed | 2024-03-13T00:14:00Z |
| format | Article |
| id | doaj.art-e38f9aacdb7846c18d6b78cecde86fd4 |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-13T00:14:00Z |
| publishDate | 2023-06-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-e38f9aacdb7846c18d6b78cecde86fd42023-07-12T07:29:01ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-06-0110.12890/2023_0039393474Alpha-gal syndrome – A case report of tick-borne anaphylactic shockJiri Muller0Jaroslav Radej1Miroslav Kriz2Eliska Hunkova3Jan Kasparek4Martin Matejovic5Department of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicDepartment of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicDepartment of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicDepartment of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicDepartment of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicDepartment of Internal Medicine, Faculty of Medicine in Pilsen, Pilsen University Hospital, Pilsen, Czech RepublicThe most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome. We present a case of a protracted life-threatening manifestation of alpha-gal syndrome, which, due to an unusual absence of typical features of anaphylaxis can masquerade as septic shock and calls attention to the premature diagnostic closure as a contributor to diagnostic error. Alpha-gal syndrome is a relatively new, but increasingly recognised health issue. We propose that alpha-gal syndrome should be considered in the differential diagnosis of vasoplegic shock of unclear aetiology even in the absence of typical allergic symptomatology and typical allergen exposure since alpha-gal is present in a wide variety of carriers.https://www.ejcrim.com/index.php/EJCRIM/article/view/3939alpha-gal syndromeanaphylactic shocksepsis mimicsmeat allergytick allergy |
| spellingShingle | Jiri Muller Jaroslav Radej Miroslav Kriz Eliska Hunkova Jan Kasparek Martin Matejovic Alpha-gal syndrome – A case report of tick-borne anaphylactic shock European Journal of Case Reports in Internal Medicine alpha-gal syndrome anaphylactic shock sepsis mimics meat allergy tick allergy |
| title | Alpha-gal syndrome – A case report of tick-borne anaphylactic shock |
| title_full | Alpha-gal syndrome – A case report of tick-borne anaphylactic shock |
| title_fullStr | Alpha-gal syndrome – A case report of tick-borne anaphylactic shock |
| title_full_unstemmed | Alpha-gal syndrome – A case report of tick-borne anaphylactic shock |
| title_short | Alpha-gal syndrome – A case report of tick-borne anaphylactic shock |
| title_sort | alpha gal syndrome a case report of tick borne anaphylactic shock |
| topic | alpha-gal syndrome anaphylactic shock sepsis mimics meat allergy tick allergy |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/3939 |
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