Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

Abstract Background Our previous work revealed that rhomboid domain-containing protein 1 (RHBDD1) participates in the modulation of cell growth and apoptosis in colorectal cancer cells. This study aimed to investigate the function of RHBDD1 in regulating breast cancer progression and its underlying...

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Bibliographic Details
Main Authors: Xin Zhang, Yuechao Zhao, Changjun Wang, Hongge Ju, Wenjie Liu, Xiaohui Zhang, Shiying Miao, Linfang Wang, Qiang Sun, Wei Song
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Cell Communication and Signaling
Subjects:
RHBDD1
Breast cancer
P-Akt
CDK2
Cell cycle progression
G1/S phase transition
Online Access:http://link.springer.com/article/10.1186/s12964-018-0267-5

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