Deficiency of ataxia‐telangiectasia mutated kinase attenuates Western‐type diet‐induced cardiac dysfunction in female mice

Deficiency of ataxia‐telangiectasia mutated kinase attenuates Western‐type diet‐induced cardiac dysfunction in female mice

Abstract Chronic consumption of Western‐type diet (WD) induces cardiac structural and functional abnormalities. Previously, we have shown that WD consumption in male ATM (ataxia‐telangiectasia mutated kinase) deficient mice associates with accelerated body weight (BW) gain, cardiac systolic dysfunct...

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Bibliographic Details
Main Authors: Mary C. Wingard, Suman Dalal, Paige L. Shook, Paulina Ramirez, Muhammad U. Raza, Patrick Johnson, Barbara A. Connelly, Douglas P. Thewke, Mahipal Singh, Krishna Singh
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Physiological Reports
Subjects:
apoptosis
ATM
female
heart
Western‐type diet
Online Access:https://doi.org/10.14814/phy2.15434

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