Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis
Background: Dumping syndrome is a common complication of surgical treatment of gastric cancer, but conventional therapy has limitations related to symptom care due to its structural cause and the decreased quality of life. Objectives: The objective of this review was to assess the clinical evidence...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-09-01
|
| Series: | Integrative Cancer Therapies |
| Online Access: | https://doi.org/10.1177/1534735419873404 |
| _version_ | 1818117779241304064 |
|---|---|
| author | Seungcheol Hong KMD Bongki Park KMD, PhD Hyeonseok Noh KMD Dong-Jun Choi KMD, PhD |
| author_facet | Seungcheol Hong KMD Bongki Park KMD, PhD Hyeonseok Noh KMD Dong-Jun Choi KMD, PhD |
| author_sort | Seungcheol Hong KMD |
| collection | DOAJ |
| description | Background: Dumping syndrome is a common complication of surgical treatment of gastric cancer, but conventional therapy has limitations related to symptom care due to its structural cause and the decreased quality of life. Objectives: The objective of this review was to assess the clinical evidence for the effectiveness of herbal medicine as a treatment for dumping syndrome. Methods: A literature review was conducted using 16 databases from their inceptions to March 2018. All randomized controlled trials (RCTs) of herbal medicine used to treat dumping syndrome patients were included and meta-analyzed. Methodological quality was assessed using the Cochrane Handbook for Systematic Reviews of Interventions. Results: A total of 174 dumping syndrome patients of 3 trials met all inclusion criteria. Two trials assessed the effectiveness of herbal medicine on the symptom response rate compared with conventional pharmacotherapy. Their results suggested significant effects in favor of herbal medicine (risk ratio [RR] = 1.37, 95% confidence interval [CI] = 1.16-1.63, P = .0003, heterogeneity τ 2 = 0, χ 2 = 0.02, P = .88, I 2 = 0%). One trial assessed its effectiveness on the improvement rate of overall symptoms compared with conventional conservative complex therapy, such as postural management, diet regulation, and counseling (RR = 1.23, 95% CI = 0.96-1.58). Conclusions: Due to the small sample size, scarcity of reported articles, and lack of quality of the current RCTs, it was concluded that the effectiveness of herbal medicine in treating dumping syndrome is unclear. |
| first_indexed | 2024-12-11T04:43:50Z |
| format | Article |
| id | doaj.art-e39db07e1c204d7d88ffddeaef230145 |
| institution | Directory Open Access Journal |
| issn | 1552-695X |
| language | English |
| last_indexed | 2024-12-11T04:43:50Z |
| publishDate | 2019-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Integrative Cancer Therapies |
| spelling | doaj.art-e39db07e1c204d7d88ffddeaef2301452022-12-22T01:20:33ZengSAGE PublishingIntegrative Cancer Therapies1552-695X2019-09-011810.1177/1534735419873404Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-AnalysisSeungcheol Hong KMD0Bongki Park KMD, PhD1Hyeonseok Noh KMD2Dong-Jun Choi KMD, PhD3Ilsan Oriental Hospital, Dongguk University Medical Centre, Goyang-si, Gyeonggi-do, Republic of KoreaMirae Korean Medicine Clinic, Cheonan-si, Chungcheongnam-do, Republic of KoreaKyung Hee University, Seoul, Republic of KoreaIlsan Oriental Hospital, Dongguk University Medical Centre, Goyang-si, Gyeonggi-do, Republic of KoreaBackground: Dumping syndrome is a common complication of surgical treatment of gastric cancer, but conventional therapy has limitations related to symptom care due to its structural cause and the decreased quality of life. Objectives: The objective of this review was to assess the clinical evidence for the effectiveness of herbal medicine as a treatment for dumping syndrome. Methods: A literature review was conducted using 16 databases from their inceptions to March 2018. All randomized controlled trials (RCTs) of herbal medicine used to treat dumping syndrome patients were included and meta-analyzed. Methodological quality was assessed using the Cochrane Handbook for Systematic Reviews of Interventions. Results: A total of 174 dumping syndrome patients of 3 trials met all inclusion criteria. Two trials assessed the effectiveness of herbal medicine on the symptom response rate compared with conventional pharmacotherapy. Their results suggested significant effects in favor of herbal medicine (risk ratio [RR] = 1.37, 95% confidence interval [CI] = 1.16-1.63, P = .0003, heterogeneity τ 2 = 0, χ 2 = 0.02, P = .88, I 2 = 0%). One trial assessed its effectiveness on the improvement rate of overall symptoms compared with conventional conservative complex therapy, such as postural management, diet regulation, and counseling (RR = 1.23, 95% CI = 0.96-1.58). Conclusions: Due to the small sample size, scarcity of reported articles, and lack of quality of the current RCTs, it was concluded that the effectiveness of herbal medicine in treating dumping syndrome is unclear.https://doi.org/10.1177/1534735419873404 |
| spellingShingle | Seungcheol Hong KMD Bongki Park KMD, PhD Hyeonseok Noh KMD Dong-Jun Choi KMD, PhD Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis Integrative Cancer Therapies |
| title | Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis |
| title_full | Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis |
| title_fullStr | Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis |
| title_short | Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis |
| title_sort | herbal medicine for dumping syndrome a systematic review and meta analysis |
| url | https://doi.org/10.1177/1534735419873404 |
| work_keys_str_mv | AT seungcheolhongkmd herbalmedicinefordumpingsyndromeasystematicreviewandmetaanalysis AT bongkiparkkmdphd herbalmedicinefordumpingsyndromeasystematicreviewandmetaanalysis AT hyeonseoknohkmd herbalmedicinefordumpingsyndromeasystematicreviewandmetaanalysis AT dongjunchoikmdphd herbalmedicinefordumpingsyndromeasystematicreviewandmetaanalysis |