Differential impact of body mass index and leptin on baseline and longitudinal positron emission tomography measurements of the cerebral metabolic rate for glucose in amnestic mild cognitive impairment

Differential impact of body mass index and leptin on baseline and longitudinal positron emission tomography measurements of the cerebral metabolic rate for glucose in amnestic mild cognitive impairment

IntroductionSeveral studies have suggested that greater adiposity in older adults is associated with a lower risk of Alzheimer’s disease (AD) related cognitive decline, some investigators have postulated that this association may be due to the protective effects of the adipose tissue-derived hormone...

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Bibliographic Details
Main Authors: Christopher M. Weise, Kewei Chen, Yinghua Chen, Vivek Devadas, Yi Su, Eric M. Reiman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
BMI
leptin
FDG-PET
regional cerebral metabolic rate for glucose (rCMRgl)
mild cognitive impairment (MCI)
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1031189/full

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