The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome

The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome

Acute Promyelocytic Leukemia (APL) is characterized by the t(15;17) chromosomal translocation resulting in a PML-RARA fusion protein. The all-trans-retinoic acid (ATRA) and Arsenic Trioxide (ATO) only regimens have demonstrated success in treating low- and intermediate-risk patients. However, induct...

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Bibliographic Details
Main Authors:	Dominic LaBella, Samuel Regan, Heiko Konig, Daniel N. Egan, Neil A. Bailey, Raya Mawad, Morgan Gilbert, John M. Pagel, Jeffrey J. Pu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Oncology
Subjects:	Acute Promyelocytic Leukemia All-Trans-Retinoic Acid (ATRA) Arsenic Trioxide (ATO) Differentiation Syndrome (DS) Adjuvant Chemotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.911745/full

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