BMSC Transplantation Aggravates Inflammation, Oxidative Stress, and Fibrosis and Impairs Skeletal Muscle Regeneration

BMSC Transplantation Aggravates Inflammation, Oxidative Stress, and Fibrosis and Impairs Skeletal Muscle Regeneration

Skeletal muscle contusion is one of the most common muscle injuries in sports medicine and traumatology. Bone marrow mesenchymal stem cell (BMSC) transplantation has been proposed as a promising strategy to promote skeletal muscle regeneration. However, the roles and underlying mechanisms of BMSCs i...

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Bibliographic Details
Main Authors: Xiaoguang Liu, Lifang Zheng, Yongzhan Zhou, Yingjie Chen, Peijie Chen, Weihua Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
bone marrow mesenchymal stem cells
skeletal muscle
regeneration
inflammation
oxidative stress
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00087/full

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