Epidermal growth factor/epidermal growth factor receptor signaling axis is a significant regulator of the proteasome expression and activity in colon cancer cells

Colon cancer is the third most common type of cancer worldwide. Epidermal growth factor receptor (EGFR) plays a crucial role in the (patho)physiology of the disease. EGFR controls vital cellular processes, while this action is associated with poor prognosis. In addition, K-Ras mutations are associat...

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Bibliographic Details
Format: Article
Language:English
Published: ScienceOpen 2014-09-01
Series:ScienceOpen Research
Online Access:https://www.scienceopen.com/document?vid=0003c012-d129-47a7-95ca-23a5647cd8e8