Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol
Introduction Psychosocial interventions for people experiencing early and emerging psychosis have demonstrated efficacy in reducing symptom severity and supporting recovery; however, much remains unknown about optimising treatment and future research trials are required. Gaining a better understandi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/9/e060863.full |
| _version_ | 1811210663654064128 |
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| author | Bróna Nic Giolla Easpaig Richard Gray Daniel Bressington Jianxia Zhai Ellie Brown |
| author_facet | Bróna Nic Giolla Easpaig Richard Gray Daniel Bressington Jianxia Zhai Ellie Brown |
| author_sort | Bróna Nic Giolla Easpaig |
| collection | DOAJ |
| description | Introduction Psychosocial interventions for people experiencing early and emerging psychosis have demonstrated efficacy in reducing symptom severity and supporting recovery; however, much remains unknown about optimising treatment and future research trials are required. Gaining a better understanding of feasibility in trials of psychosocial interventions involving this population would inform the design and planning of future research and support the development of high-quality evidence. The aim of this systematic review is to evaluate the recruitment rate, study attrition rates and intervention completion of psychosocial intervention randomised controlled trial studies involving people with early and emerging psychosis.Methods and analysis The systematic review will be reported in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols 2015 guideline. The Cochrane Library, PubMed, Medline, PsycINFO, Web of Science and CINAHL databases will be searched from inception to September 2021 to identify potentially relevant studies. The title and abstracts of returned records will be assessed for eligibility against the inclusion/exclusion criteria by two reviewers, independently, and records which appear eligible will be included. The full texts of included records will then be assessed using the same procedure. Qualitative and quantitative synthesis will be undertaken. Proportion meta-analyses will be used to calculate the recruitment rate, study attrition rate and intervention completion rate, while subgroup analyses will explore differences among subgroups of study and intervention characteristics.Ethics and dissemination This study will collate and analyse anonymised data from published research and therefore, ethical approval is not necessary. Study results will be disseminated via publication in academic journals. |
| first_indexed | 2024-04-12T04:59:38Z |
| format | Article |
| id | doaj.art-e3aaa8837b2b41948cb0ca865883e23c |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-12T04:59:38Z |
| publishDate | 2022-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-e3aaa8837b2b41948cb0ca865883e23c2022-12-22T03:47:02ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2022-060863Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocolBróna Nic Giolla Easpaig0Richard Gray1Daniel Bressington2Jianxia Zhai3Ellie Brown4College of Nursing and Midwifery, Charles Darwin University, Casuarina, Darwin, AustraliaSchool of Nursing, La Trobe University, Bundoora, Victoria, AustraliaCollege of Nursing & Midwifery, Charles Darwin University, Casuarina, Northern Territory, AustraliaCollege of Nursing & Midwifery, Charles Darwin University, Casuarina, Northern Territory, AustraliaCentre for Youth Mental Health, Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, AustraliaIntroduction Psychosocial interventions for people experiencing early and emerging psychosis have demonstrated efficacy in reducing symptom severity and supporting recovery; however, much remains unknown about optimising treatment and future research trials are required. Gaining a better understanding of feasibility in trials of psychosocial interventions involving this population would inform the design and planning of future research and support the development of high-quality evidence. The aim of this systematic review is to evaluate the recruitment rate, study attrition rates and intervention completion of psychosocial intervention randomised controlled trial studies involving people with early and emerging psychosis.Methods and analysis The systematic review will be reported in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols 2015 guideline. The Cochrane Library, PubMed, Medline, PsycINFO, Web of Science and CINAHL databases will be searched from inception to September 2021 to identify potentially relevant studies. The title and abstracts of returned records will be assessed for eligibility against the inclusion/exclusion criteria by two reviewers, independently, and records which appear eligible will be included. The full texts of included records will then be assessed using the same procedure. Qualitative and quantitative synthesis will be undertaken. Proportion meta-analyses will be used to calculate the recruitment rate, study attrition rate and intervention completion rate, while subgroup analyses will explore differences among subgroups of study and intervention characteristics.Ethics and dissemination This study will collate and analyse anonymised data from published research and therefore, ethical approval is not necessary. Study results will be disseminated via publication in academic journals.https://bmjopen.bmj.com/content/12/9/e060863.full |
| spellingShingle | Bróna Nic Giolla Easpaig Richard Gray Daniel Bressington Jianxia Zhai Ellie Brown Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol BMJ Open |
| title | Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol |
| title_full | Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol |
| title_fullStr | Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol |
| title_full_unstemmed | Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol |
| title_short | Recruitment, attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis: a systematic review protocol |
| title_sort | recruitment attrition and intervention completion in clinical trials of psychosocial interventions involving people with early and emerging psychosis a systematic review protocol |
| url | https://bmjopen.bmj.com/content/12/9/e060863.full |
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