DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell‐rich histological mimics

DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell‐rich histological mimics

Abstract Sporadic giant cell granulomas (GCGs) of the jaws and cherubism‐associated giant cell lesions share histopathological features and microscopic diagnosis alone can be challenging. Additionally, GCG can morphologically closely resemble other giant cell‐rich lesions, including non‐ossifying fi...

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Bibliographic Details
Main Authors: Letícia Martins Guimarães, Daniel Baumhoer, Vanghelita Andrei, Dennis Friedel, Christian Koelsche, Ricardo Santiago Gomez, Andreas von Deimling, Carolina Cavalieri Gomes
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:The Journal of Pathology: Clinical Research
Subjects:
epigenetics
DNA methylation
copy number analysis
giant cell granulomas
cherubism
aneurysmal bone cyst
Online Access:https://doi.org/10.1002/cjp2.337

Internet

https://doi.org/10.1002/cjp2.337

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