Atypical, non-standard functions of the microtubule associated Tau protein

Atypical, non-standard functions of the microtubule associated Tau protein

Abstract Since the discovery of the microtubule-associated protein Tau (MAPT) over 40 years ago, most studies have focused on Tau’s role in microtubule stability and regulation, as well as on the neuropathological consequences of Tau hyperphosphorylation and aggregation in Alzheimer’s disease (AD) b...

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Bibliographic Details
Main Authors: Ioannis Sotiropoulos, Marie-Christine Galas, Joana M. Silva, Efthimios Skoulakis, Susanne Wegmann, Mahmoud Bukar Maina, David Blum, Carmen Laura Sayas, Eva-Maria Mandelkow, Eckhard Mandelkow, Maria Grazia Spillantini, Nuno Sousa, Jesus Avila, Miguel Medina, Amrit Mudher, Luc Buee
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Acta Neuropathologica Communications
Subjects:
Tau
Alzheimer’s disease
Neuronal function
Pathology
Nucleus
Dendrites
Online Access:http://link.springer.com/article/10.1186/s40478-017-0489-6

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