Effect of inhaled and oral n-acetylcysteine on airway defense mechanism

Aim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiologi...

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Main Authors: Pappová L., Kazimierová I., Kocmálová M.
Format: Article
Language:English
Published: Sciendo 2017-09-01
Series:European Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.1515/afpuc-2017-0002
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author Pappová L.
Kazimierová I.
Kocmálová M.
author_facet Pappová L.
Kazimierová I.
Kocmálová M.
author_sort Pappová L.
collection DOAJ
description Aim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiological conditions.
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spelling doaj.art-e3b12c50b1ab44dbb186eae375fea1fa2022-12-21T21:35:29ZengSciendoEuropean Pharmaceutical Journal2453-67252017-09-01641172110.1515/afpuc-2017-0002Effect of inhaled and oral n-acetylcysteine on airway defense mechanismPappová L.0Kazimierová I.1Kocmálová M.2Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicAim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiological conditions.https://doi.org/10.1515/afpuc-2017-0002n-acetylcysteinemucus clearanceciliary beat frequencyairway reactivity
spellingShingle Pappová L.
Kazimierová I.
Kocmálová M.
Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
European Pharmaceutical Journal
n-acetylcysteine
mucus clearance
ciliary beat frequency
airway reactivity
title Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
title_full Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
title_fullStr Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
title_full_unstemmed Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
title_short Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
title_sort effect of inhaled and oral n acetylcysteine on airway defense mechanism
topic n-acetylcysteine
mucus clearance
ciliary beat frequency
airway reactivity
url https://doi.org/10.1515/afpuc-2017-0002
work_keys_str_mv AT pappoval effectofinhaledandoralnacetylcysteineonairwaydefensemechanism
AT kazimierovai effectofinhaledandoralnacetylcysteineonairwaydefensemechanism
AT kocmalovam effectofinhaledandoralnacetylcysteineonairwaydefensemechanism