Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
Aim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiologi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Sciendo
2017-09-01
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Series: | European Pharmaceutical Journal |
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Online Access: | https://doi.org/10.1515/afpuc-2017-0002 |
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author | Pappová L. Kazimierová I. Kocmálová M. |
author_facet | Pappová L. Kazimierová I. Kocmálová M. |
author_sort | Pappová L. |
collection | DOAJ |
description | Aim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiological conditions. |
first_indexed | 2024-12-17T19:21:54Z |
format | Article |
id | doaj.art-e3b12c50b1ab44dbb186eae375fea1fa |
institution | Directory Open Access Journal |
issn | 2453-6725 |
language | English |
last_indexed | 2024-12-17T19:21:54Z |
publishDate | 2017-09-01 |
publisher | Sciendo |
record_format | Article |
series | European Pharmaceutical Journal |
spelling | doaj.art-e3b12c50b1ab44dbb186eae375fea1fa2022-12-21T21:35:29ZengSciendoEuropean Pharmaceutical Journal2453-67252017-09-01641172110.1515/afpuc-2017-0002Effect of inhaled and oral n-acetylcysteine on airway defense mechanismPappová L.0Kazimierová I.1Kocmálová M.2Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Martin, Slovak RepublicAim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned defense mechanisms were assessed in physiological conditions.https://doi.org/10.1515/afpuc-2017-0002n-acetylcysteinemucus clearanceciliary beat frequencyairway reactivity |
spellingShingle | Pappová L. Kazimierová I. Kocmálová M. Effect of inhaled and oral n-acetylcysteine on airway defense mechanism European Pharmaceutical Journal n-acetylcysteine mucus clearance ciliary beat frequency airway reactivity |
title | Effect of inhaled and oral n-acetylcysteine on airway defense mechanism |
title_full | Effect of inhaled and oral n-acetylcysteine on airway defense mechanism |
title_fullStr | Effect of inhaled and oral n-acetylcysteine on airway defense mechanism |
title_full_unstemmed | Effect of inhaled and oral n-acetylcysteine on airway defense mechanism |
title_short | Effect of inhaled and oral n-acetylcysteine on airway defense mechanism |
title_sort | effect of inhaled and oral n acetylcysteine on airway defense mechanism |
topic | n-acetylcysteine mucus clearance ciliary beat frequency airway reactivity |
url | https://doi.org/10.1515/afpuc-2017-0002 |
work_keys_str_mv | AT pappoval effectofinhaledandoralnacetylcysteineonairwaydefensemechanism AT kazimierovai effectofinhaledandoralnacetylcysteineonairwaydefensemechanism AT kocmalovam effectofinhaledandoralnacetylcysteineonairwaydefensemechanism |