Sex differences in a double-blind randomized clinical trial with minocycline in treatment-resistant depressed patients: CRP and IL-6 as sex-specific predictors of treatment response

Background: Inflammation is a well-known risk factor for depression. Specifically, patients who do not respond to antidepressant treatment show higher levels of inflammatory biomarkers compared with responders. Thus, several studies have investigated the efficacy of anti-inflammatory add-on treatmen...

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Main Authors: Giulia Lombardo, Maria Antonietta Nettis, Caitlin Hastings, Zuzanna Zajkowska, Nicole Mariani, Naghmeh Nikkheslat, Courtney Worrell, Daniela Enache, Anna McLaughlin, Melisa Kose, Anna Bogdanova, Luca Sforzini, Anthony J. Cleare, Allan H. Young, Paola Dazzan, Valeria Mondelli, Carmine M. Pariante
格式: 文件
语言:English
出版: Elsevier 2022-12-01
丛编:Brain, Behavior, & Immunity - Health
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在线阅读:http://www.sciencedirect.com/science/article/pii/S266635462200151X