Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat

A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physi...

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Main Authors: D’Andrea Cristiano, Banchelli Martina, Amicucci Chiara, Polykretis Panagis, Micheletti Filippo, de Angelis Marella, Hwang Byungil, Matteini Paolo
Format: Article
Language:English
Published: EDP Sciences 2024-01-01
Series:Journal of the European Optical Society-Rapid Publications
Subjects:
Online Access:https://jeos.edpsciences.org/articles/jeos/full_html/2024/01/jeos20240004/jeos20240004.html
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author D’Andrea Cristiano
Banchelli Martina
Amicucci Chiara
Polykretis Panagis
Micheletti Filippo
de Angelis Marella
Hwang Byungil
Matteini Paolo
author_facet D’Andrea Cristiano
Banchelli Martina
Amicucci Chiara
Polykretis Panagis
Micheletti Filippo
de Angelis Marella
Hwang Byungil
Matteini Paolo
author_sort D’Andrea Cristiano
collection DOAJ
description A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physiologic concentrations in combination with the pH measurement in the range between 5 and 9. Once integrated with commercial biocompatible and adhesive tape layers, the as produced SERS-active chip provides a low-cost, flexible and wearable sensing device for rapid and reliable human sweat analysis. The chip was finally tested on real sweat samples to estimate lactate and urea during medium-intense exertions.
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spelling doaj.art-e3b40bf69ae14d1aada0fcc103020a7d2024-04-17T09:13:56ZengEDP SciencesJournal of the European Optical Society-Rapid Publications1990-25732024-01-012011010.1051/jeos/2024013jeos20240004Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweatD’Andrea Cristiano0https://orcid.org/0000-0001-5807-3067Banchelli Martina1https://orcid.org/0000-0001-5348-0552Amicucci Chiara2Polykretis Panagis3https://orcid.org/0000-0001-7911-1691Micheletti Filippo4https://orcid.org/0000-0002-6638-1577de Angelis Marella5https://orcid.org/0000-0001-7057-8340Hwang Byungil6Matteini Paolo7https://orcid.org/0000-0002-8488-5867Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)School of Integrative Engineering, Chung-Ang UniversityInstitute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR)A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physiologic concentrations in combination with the pH measurement in the range between 5 and 9. Once integrated with commercial biocompatible and adhesive tape layers, the as produced SERS-active chip provides a low-cost, flexible and wearable sensing device for rapid and reliable human sweat analysis. The chip was finally tested on real sweat samples to estimate lactate and urea during medium-intense exertions.https://jeos.edpsciences.org/articles/jeos/full_html/2024/01/jeos20240004/jeos20240004.htmlwearable sensorserssweaturealactatephsilver nanowires
spellingShingle D’Andrea Cristiano
Banchelli Martina
Amicucci Chiara
Polykretis Panagis
Micheletti Filippo
de Angelis Marella
Hwang Byungil
Matteini Paolo
Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
Journal of the European Optical Society-Rapid Publications
wearable sensor
sers
sweat
urea
lactate
ph
silver nanowires
title Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
title_full Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
title_fullStr Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
title_full_unstemmed Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
title_short Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat
title_sort development of a wearable surface enhanced raman scattering sensor chip based on silver nanowires for rapid detection of urea lactate and ph in sweat
topic wearable sensor
sers
sweat
urea
lactate
ph
silver nanowires
url https://jeos.edpsciences.org/articles/jeos/full_html/2024/01/jeos20240004/jeos20240004.html
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