Handling method affects measures of anxiety, but not chronic stress in mice
Abstract Studies in mice have shown that less aversive handling methods (e.g. tunnel or cup handling) can reduce behavioural measures of anxiety in comparison to picking mice up by their tail. Despite such evidence, tail handling continues to be used routinely. Besides resistance to change accustome...
Main Authors: | Janja Novak, Ivana Jaric, Marianna Rosso, Reto Rufener, Chadi Touma, Hanno Würbel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-12-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-25090-9 |
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