Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines
A simple physical technique was used in this study to create stable and cost-effective copper oxide (CuO) nanoparticles from pure copper metal using the pulsed laser ablation technique. The synthesis of crystalline CuO nanoparticles was confirmed by various analytical techniques such as particle co...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2023-06-01
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| Series: | Iraqi Journal of Physics |
| Subjects: | |
| Online Access: | https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1092 |
| _version_ | 1797810742843408384 |
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| author | Huda Hussein Abbas Sabah N. Mazhir |
| author_facet | Huda Hussein Abbas Sabah N. Mazhir |
| author_sort | Huda Hussein Abbas |
| collection | DOAJ |
| description |
A simple physical technique was used in this study to create stable and cost-effective copper oxide (CuO) nanoparticles from pure copper metal using the pulsed laser ablation technique. The synthesis of crystalline CuO nanoparticles was confirmed by various analytical techniques such as particle concentration measurement using atomic absorption spectrometry (AAS), field emission scanning electron microscopy (FE-SEM), the energy dispersive X-ray (EDX), and X-ray diffraction (XRD) to determine the crystal size and identify of the crystal structure of the prepared particles. The main characteristic diffraction peaks of the three samples were consistent. The corresponding 2θ is also consistent, and the cytotoxicity of the nanoparticles was also investigated. After 24 hours of exposure, the percentage of cytotoxicity was calculated. The maximum toxicity of Hep-G2 was 37.81% at the maximum concentration of (500) µg mL-1 after 24 hours of exposure. Also, the maximum toxicity of the normal cell line was 27.85% at a maximum concentration of (500) µg mL-1.
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| first_indexed | 2024-03-13T07:13:27Z |
| format | Article |
| id | doaj.art-e3b89de9758240c1882e3a8e324da658 |
| institution | Directory Open Access Journal |
| issn | 2070-4003 2664-5548 |
| language | English |
| last_indexed | 2024-03-13T07:13:27Z |
| publishDate | 2023-06-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Iraqi Journal of Physics |
| spelling | doaj.art-e3b89de9758240c1882e3a8e324da6582023-06-05T16:56:34ZengUniversity of BaghdadIraqi Journal of Physics2070-40032664-55482023-06-0121210.30723/ijp.v21i2.1092Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell LinesHuda Hussein AbbasSabah N. Mazhir A simple physical technique was used in this study to create stable and cost-effective copper oxide (CuO) nanoparticles from pure copper metal using the pulsed laser ablation technique. The synthesis of crystalline CuO nanoparticles was confirmed by various analytical techniques such as particle concentration measurement using atomic absorption spectrometry (AAS), field emission scanning electron microscopy (FE-SEM), the energy dispersive X-ray (EDX), and X-ray diffraction (XRD) to determine the crystal size and identify of the crystal structure of the prepared particles. The main characteristic diffraction peaks of the three samples were consistent. The corresponding 2θ is also consistent, and the cytotoxicity of the nanoparticles was also investigated. After 24 hours of exposure, the percentage of cytotoxicity was calculated. The maximum toxicity of Hep-G2 was 37.81% at the maximum concentration of (500) µg mL-1 after 24 hours of exposure. Also, the maximum toxicity of the normal cell line was 27.85% at a maximum concentration of (500) µg mL-1. https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1092CuO NPsPLALliver CancerHdFn cell linesPhotoluminescence |
| spellingShingle | Huda Hussein Abbas Sabah N. Mazhir Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines Iraqi Journal of Physics CuO NPs PLAL liver Cancer HdFn cell lines Photoluminescence |
| title | Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines |
| title_full | Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines |
| title_fullStr | Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines |
| title_full_unstemmed | Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines |
| title_short | Cytotoxic Activity of CuO NPs Prepared by PLAL Against Liver Cancer (Hep-G2) Cell Line and HdFn Cell Lines |
| title_sort | cytotoxic activity of cuo nps prepared by plal against liver cancer hep g2 cell line and hdfn cell lines |
| topic | CuO NPs PLAL liver Cancer HdFn cell lines Photoluminescence |
| url | https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1092 |
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