The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence

The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence

There is evidence that accumulated senescent cells drive age-related pathologies, but the antecedents to the cellular stressors that induce senescence remain poorly understood. Previous research suggests that there is a relationship between shorter telomere length, an antecedent to cellular senescen...

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Bibliographic Details
Main Authors: Torvald F. Ask, Ricardo G. Lugo, Stefan Sütterlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Neuroscience
Subjects:
heart rate variability
cytokines
telomere damage
NFkB
cellular senescence
reactive oxygen species
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00726/full

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