Synthesis and biological properties of hemin conjugates with unprotected peptides.

Synthesis and biological properties of hemin conjugates with unprotected peptides.

Arginine-containing peptides consisted of 3- and 13- amino acids residues, namely RGD and [5Ala]-indolicidine were synthetized. Monosubstituted hemin derivatives modificated by RGD, [5Ala]-indolicidine and gramicidine S were obtained. Biocide activity and low toxicity of obtained conjugates was show...

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Bibliographic Details
Main Authors: S. A. Okorochenkov, E. A. Bistrova, E. M. Pavlova, G. A. Zheltukhina, V. E. Nebolsin
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2010-10-01
Series:Тонкие химические технологии
Subjects:
hemin
antimicrobial peptides
biocide activity
Online Access:https://www.finechem-mirea.ru/jour/article/view/934

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