T cells specific for post-translational modifications escape intrathymic tolerance induction

T cells specific for post-translational modifications escape intrathymic tolerance induction

Post-translational modifications are associated with autoimmune diseases but definitive evidence of their contribution to escape from central tolerance mechanisms is needed. Here, the authors show that T cells specific for post-translational modifications of type II collagen escape intrathymic toler...

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Detalles Bibliográficos
Autores principales: Bruno Raposo, Patrick Merky, Christina Lundqvist, Hisakata Yamada, Vilma Urbonaviciute, Colin Niaudet, Johan Viljanen, Jan Kihlberg, Bruno Kyewski, Olov Ekwall, Rikard Holmdahl, Johan Bäcklund
Formato: Artículo
Lenguaje:English
Publicado: Nature Portfolio 2018-01-01
Colección:Nature Communications
Acceso en línea:https://doi.org/10.1038/s41467-017-02763-y

Internet

https://doi.org/10.1038/s41467-017-02763-y

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