Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV)
The data presented here are related to the research article entitled “Age predicts cytokine kinetics and innate immune cell activation following intranasal delivery of IFNγ and GM-CSF in a mouse model of RSV infection” (Eichinger et al., 2017) [1]. The cited manuscript demonstrated that the macropha...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-10-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340917303360 |
| _version_ | 1818269794782150656 |
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| author | Katherine M. Eichinger Kerry M. Empey |
| author_facet | Katherine M. Eichinger Kerry M. Empey |
| author_sort | Katherine M. Eichinger |
| collection | DOAJ |
| description | The data presented here are related to the research article entitled “Age predicts cytokine kinetics and innate immune cell activation following intranasal delivery of IFNγ and GM-CSF in a mouse model of RSV infection” (Eichinger et al., 2017) [1]. The cited manuscript demonstrated that the macrophage-stimulating cytokine, interferon gamma (IFNγ), but not granulocyte macrophage-colony stimulating factor (GM-CSF), effectively enhanced viral clearance in infant mice infected with respiratory syncytial virus (RSV) following intranasal delivery. This article describes the immune response and viral clearing effects of intranasal IFNγ in RSV-infected adult BALB/c mice demonstrating delayed production of endogenous IFNγ. The dataset is made publicly available to extrapolate the role of IFNγ in RSV-infected adult mice. |
| first_indexed | 2024-12-12T21:00:03Z |
| format | Article |
| id | doaj.art-e3c1090768284960bd296b7fd9110ae7 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-12T21:00:03Z |
| publishDate | 2017-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-e3c1090768284960bd296b7fd9110ae72022-12-22T00:12:11ZengElsevierData in Brief2352-34092017-10-0114C27227710.1016/j.dib.2017.07.034Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV)Katherine M. Eichinger0Kerry M. Empey1Department of Pharmacy and Therapeutics, Pittsburgh, PA, USADepartment of Pharmacy and Therapeutics, Pittsburgh, PA, USAThe data presented here are related to the research article entitled “Age predicts cytokine kinetics and innate immune cell activation following intranasal delivery of IFNγ and GM-CSF in a mouse model of RSV infection” (Eichinger et al., 2017) [1]. The cited manuscript demonstrated that the macrophage-stimulating cytokine, interferon gamma (IFNγ), but not granulocyte macrophage-colony stimulating factor (GM-CSF), effectively enhanced viral clearance in infant mice infected with respiratory syncytial virus (RSV) following intranasal delivery. This article describes the immune response and viral clearing effects of intranasal IFNγ in RSV-infected adult BALB/c mice demonstrating delayed production of endogenous IFNγ. The dataset is made publicly available to extrapolate the role of IFNγ in RSV-infected adult mice.http://www.sciencedirect.com/science/article/pii/S2352340917303360ImmunologyCytokineRSVIFNγMice |
| spellingShingle | Katherine M. Eichinger Kerry M. Empey Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) Data in Brief Immunology Cytokine RSV IFNγ Mice |
| title | Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) |
| title_full | Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) |
| title_fullStr | Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) |
| title_full_unstemmed | Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) |
| title_short | Data describing IFNγ-mediated viral clearance in an adult mouse model of respiratory syncytial virus (RSV) |
| title_sort | data describing ifnγ mediated viral clearance in an adult mouse model of respiratory syncytial virus rsv |
| topic | Immunology Cytokine RSV IFNγ Mice |
| url | http://www.sciencedirect.com/science/article/pii/S2352340917303360 |
| work_keys_str_mv | AT katherinemeichinger datadescribingifngmediatedviralclearanceinanadultmousemodelofrespiratorysyncytialvirusrsv AT kerrymempey datadescribingifngmediatedviralclearanceinanadultmousemodelofrespiratorysyncytialvirusrsv |