Diagnostic value of metagenomic next-generation sequencing of lower respiratory tract specimen for the diagnosis of suspected Pneumocystis jirovecii pneumonia

Diagnostic value of metagenomic next-generation sequencing of lower respiratory tract specimen for the diagnosis of suspected Pneumocystis jirovecii pneumonia

AbstractAim To evaluate diagnostic performance of metagenomic next-generation sequencing (mNGS) for Pneumocystis jirovecii pneumonia (PCP), in comparison with polymerase chain reaction (PCR), Gomori methenamine silver (GMS) staining and serum 1,3-β-d-Glucan (BG) assay.Methods 52 PCP patients and 103...

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Bibliographic Details
Main Authors: Yang Liu, Xiaoning Wang, Jun Xu, Qiwen Yang, Huadong Zhu, Jing Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
Pneumocystis jirovecii pneumonia
metagenomic next-generation sequencing
diagnostic performance
pathogen detection
lower respiratory tract specimen
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2232358

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