Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias

Accuracy is an important parameter of a diagnostic test. Studies that attempt to determine a test’s accuracy can suffer from various forms of bias. As radiology is a diagnostic specialty, many radiologists may design a diagnostic accuracy study or review one to understand how it may apply to their p...

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Main Authors: Athanasios Pavlou, Robert M. Kurtz, Jae W. Song
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2021/5801662
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author Athanasios Pavlou
Robert M. Kurtz
Jae W. Song
author_facet Athanasios Pavlou
Robert M. Kurtz
Jae W. Song
author_sort Athanasios Pavlou
collection DOAJ
description Accuracy is an important parameter of a diagnostic test. Studies that attempt to determine a test’s accuracy can suffer from various forms of bias. As radiology is a diagnostic specialty, many radiologists may design a diagnostic accuracy study or review one to understand how it may apply to their practice. Radiologists also frequently serve as consultants to other physicians regarding the selection of the most appropriate diagnostic exams. In these roles, understanding how to critically appraise the literature is important for all radiologists. The purpose of this review is to provide a framework for evaluating potential sources of study design biases that are found in diagnostic accuracy studies and to explain their impact on sensitivity and specificity estimates. To help the reader understand these biases, we also present examples from the radiology literature.
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spelling doaj.art-e3c731aed6984dbeb1cf7b26b0b3cef42022-12-22T04:05:36ZengHindawi LimitedRadiology Research and Practice2090-19412090-195X2021-01-01202110.1155/2021/58016625801662Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of BiasAthanasios Pavlou0Robert M. Kurtz1Jae W. Song2St. Vincent’s Medical Center, Bridgeport, CT, USAHospital of the University of Pennsylvania, Philadelphia, PA, USAHospital of the University of Pennsylvania, Philadelphia, PA, USAAccuracy is an important parameter of a diagnostic test. Studies that attempt to determine a test’s accuracy can suffer from various forms of bias. As radiology is a diagnostic specialty, many radiologists may design a diagnostic accuracy study or review one to understand how it may apply to their practice. Radiologists also frequently serve as consultants to other physicians regarding the selection of the most appropriate diagnostic exams. In these roles, understanding how to critically appraise the literature is important for all radiologists. The purpose of this review is to provide a framework for evaluating potential sources of study design biases that are found in diagnostic accuracy studies and to explain their impact on sensitivity and specificity estimates. To help the reader understand these biases, we also present examples from the radiology literature.http://dx.doi.org/10.1155/2021/5801662
spellingShingle Athanasios Pavlou
Robert M. Kurtz
Jae W. Song
Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
Radiology Research and Practice
title Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
title_full Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
title_fullStr Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
title_full_unstemmed Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
title_short Diagnostic Accuracy Studies in Radiology: How to Recognize and Address Potential Sources of Bias
title_sort diagnostic accuracy studies in radiology how to recognize and address potential sources of bias
url http://dx.doi.org/10.1155/2021/5801662
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