Bicarbonate supplementation as a preventive way in statins-induced muscle damage

Bicarbonate supplementation as a preventive way in statins-induced muscle damage

ABSTRACT – Purpose. The aim of this study was to evaluate the bicarbonate-induced improvement of statins, cerivastatin, simvastatin acid and lovastatin acid -induced apoptosis using rat myoblast cell line (L6) as a model of in vitro skeletal muscle and of cerivastatin-induced muscle damage in vivo s...

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Bibliographic Details
Main Authors: Masaki Kobayashi, Toshiki Kagawa, Katsuya Narumi, Shirou Itagaki, Takeshi Hirano, Ken Iseki
Format: Article
Language:English
Published: Frontiers Media S.A. 2008-02-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/1367

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