Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma

In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endomet...

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Bibliographic Details
Main Author: Spasimir Shopov
Format: Article
Language:English
Published: Pensoft Publishers 2020-03-01
Series:Folia Medica
Subjects:
Online Access:https://foliamedica.bg/article/49813/download/pdf/
Description
Summary:In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed.
ISSN:1314-2143