Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma

In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endomet...

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Main Author: Spasimir Shopov
Format: Article
Language:English
Published: Pensoft Publishers 2020-03-01
Series:Folia Medica
Subjects:
Online Access:https://foliamedica.bg/article/49813/download/pdf/
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author Spasimir Shopov
author_facet Spasimir Shopov
author_sort Spasimir Shopov
collection DOAJ
description In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed.
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spelling doaj.art-e3d10b2407e048f289c1f65d3efb4a102022-12-21T23:20:46ZengPensoft PublishersFolia Medica1314-21432020-03-0162119019410.3897/folmed.62.e4981349813Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a LeiomyomaSpasimir Shopov0Medical UniversityIn endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed.https://foliamedica.bg/article/49813/download/pdf/carcinomaimmunohistochemicalleiomyomauterus
spellingShingle Spasimir Shopov
Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
Folia Medica
carcinoma
immunohistochemical
leiomyoma
uterus
title Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
title_full Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
title_fullStr Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
title_full_unstemmed Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
title_short Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
title_sort papillary endometrioid carcinoma amp nbsp of intermediate grade with infiltration amp nbsp in a leiomyoma
topic carcinoma
immunohistochemical
leiomyoma
uterus
url https://foliamedica.bg/article/49813/download/pdf/
work_keys_str_mv AT spasimirshopov papillaryendometrioidcarcinomaampnbspofintermediategradewithinfiltrationampnbspinaleiomyoma