Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma
In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endomet...
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Format: | Article |
Language: | English |
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Pensoft Publishers
2020-03-01
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Series: | Folia Medica |
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Online Access: | https://foliamedica.bg/article/49813/download/pdf/ |
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author | Spasimir Shopov |
author_facet | Spasimir Shopov |
author_sort | Spasimir Shopov |
collection | DOAJ |
description | In endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed. |
first_indexed | 2024-12-14T02:10:45Z |
format | Article |
id | doaj.art-e3d10b2407e048f289c1f65d3efb4a10 |
institution | Directory Open Access Journal |
issn | 1314-2143 |
language | English |
last_indexed | 2024-12-14T02:10:45Z |
publishDate | 2020-03-01 |
publisher | Pensoft Publishers |
record_format | Article |
series | Folia Medica |
spelling | doaj.art-e3d10b2407e048f289c1f65d3efb4a102022-12-21T23:20:46ZengPensoft PublishersFolia Medica1314-21432020-03-0162119019410.3897/folmed.62.e4981349813Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a LeiomyomaSpasimir Shopov0Medical UniversityIn endometrioid cancer cases, the depth of myometrial invasion, the lymphovascular space invasion (LVSI) and the microcystic, elongated, and fragmented (MELF) glands type of invasion are predictors for a metastasis. Although the intermediate grade papillary endometrioid adenocarcinoma of the endometrium is currently not included in the latest classification of the tumors in the female reproductive system, its existence provokes an interest due to the necessity to perform differential diagnosis against other endometrioid tumors. Hereby presented is a case of papillary endometrioid carcinoma of intermediate grade with invasion in leiomyoma, expressed via LVSI and MELF syndrome with intact myometrium. Morphological and immunohistochemical algorithms have been performed.https://foliamedica.bg/article/49813/download/pdf/carcinomaimmunohistochemicalleiomyomauterus |
spellingShingle | Spasimir Shopov Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma Folia Medica carcinoma immunohistochemical leiomyoma uterus |
title | Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma |
title_full | Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma |
title_fullStr | Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma |
title_full_unstemmed | Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma |
title_short | Papillary Endometrioid Carcinoma of Intermediate Grade with Infiltration in a Leiomyoma |
title_sort | papillary endometrioid carcinoma amp nbsp of intermediate grade with infiltration amp nbsp in a leiomyoma |
topic | carcinoma immunohistochemical leiomyoma uterus |
url | https://foliamedica.bg/article/49813/download/pdf/ |
work_keys_str_mv | AT spasimirshopov papillaryendometrioidcarcinomaampnbspofintermediategradewithinfiltrationampnbspinaleiomyoma |