Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study
Background:. Liposuction is the most common aesthetic surgical procedure performed globally. Some of the patients with normal weight who seek liposuction may suffer from body dysmorphic disorder (BDD). Leptin, which is mainly produced by adipose tissue, may be associated with this condition. The aim...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2019-10-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002482 |
| _version_ | 1828784971291033600 |
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| author | Chatchai Pruksapong, MD, FRCST Supat Chamnanchanunt, MD Vipa Thanachartwet, MD Varunee Desakorn, MPH, MSc Daochompu Nakawiro, MD Duangjai Sahassananda, MSc Ponlapat Rojnuckarin, MD, PhD |
| author_facet | Chatchai Pruksapong, MD, FRCST Supat Chamnanchanunt, MD Vipa Thanachartwet, MD Varunee Desakorn, MPH, MSc Daochompu Nakawiro, MD Duangjai Sahassananda, MSc Ponlapat Rojnuckarin, MD, PhD |
| author_sort | Chatchai Pruksapong, MD, FRCST |
| collection | DOAJ |
| description | Background:. Liposuction is the most common aesthetic surgical procedure performed globally. Some of the patients with normal weight who seek liposuction may suffer from body dysmorphic disorder (BDD). Leptin, which is mainly produced by adipose tissue, may be associated with this condition. The aim of this study was to determine the prevalence of BDD and leptin levels in patients with normal weight seeking liposuction.
Methods:. Thirty-two nonobese women who sought liposuction were matched with 32 healthy volunteers by age and body mass index. Blood biochemistry, leptin levels, and BDD-Yale–Brown Obsessive-Compulsive Scale (BDD-YBOCS) questionnaires were evaluated and compared between the groups.
Results:. Patients who underwent liposuction had significantly higher median (interquartile range) of total BDD-YBOCS scores than healthy volunteers [25 (22–27) versus 12 (8–20); P < 0.001]. Overall, 28 (87.5%) patients had total BDD-YBOCS scores of >20, whereas 10 (31.5%) volunteers had scores of >20. Patients with total BDD-YBOCS scores of >20 had significantly lower levels of serum leptin [12.43 (7.15–16.98) ng/ml versus 15.57 (9.59–22.28) ng/ml; P = 0.043].
Conclusions:. Patients who underwent liposuction had a significantly higher total score of BDD-YBOCS than healthy volunteers matched by sex, age, and body mass index. Subjects with higher BDD-YBOCS scores had significantly lower serum leptin levels. |
| first_indexed | 2024-12-11T23:41:22Z |
| format | Article |
| id | doaj.art-e3d11cea98cc4ad38892a7f41732da34 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-11T23:41:22Z |
| publishDate | 2019-10-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-e3d11cea98cc4ad38892a7f41732da342022-12-22T00:45:44ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742019-10-01710e248210.1097/GOX.0000000000002482201910000-00003Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case StudyChatchai Pruksapong, MD, FRCST0Supat Chamnanchanunt, MD1Vipa Thanachartwet, MD2Varunee Desakorn, MPH, MSc3Daochompu Nakawiro, MD4Duangjai Sahassananda, MSc5Ponlapat Rojnuckarin, MD, PhD6From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.From Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thiland.Background:. Liposuction is the most common aesthetic surgical procedure performed globally. Some of the patients with normal weight who seek liposuction may suffer from body dysmorphic disorder (BDD). Leptin, which is mainly produced by adipose tissue, may be associated with this condition. The aim of this study was to determine the prevalence of BDD and leptin levels in patients with normal weight seeking liposuction. Methods:. Thirty-two nonobese women who sought liposuction were matched with 32 healthy volunteers by age and body mass index. Blood biochemistry, leptin levels, and BDD-Yale–Brown Obsessive-Compulsive Scale (BDD-YBOCS) questionnaires were evaluated and compared between the groups. Results:. Patients who underwent liposuction had significantly higher median (interquartile range) of total BDD-YBOCS scores than healthy volunteers [25 (22–27) versus 12 (8–20); P < 0.001]. Overall, 28 (87.5%) patients had total BDD-YBOCS scores of >20, whereas 10 (31.5%) volunteers had scores of >20. Patients with total BDD-YBOCS scores of >20 had significantly lower levels of serum leptin [12.43 (7.15–16.98) ng/ml versus 15.57 (9.59–22.28) ng/ml; P = 0.043]. Conclusions:. Patients who underwent liposuction had a significantly higher total score of BDD-YBOCS than healthy volunteers matched by sex, age, and body mass index. Subjects with higher BDD-YBOCS scores had significantly lower serum leptin levels.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002482 |
| spellingShingle | Chatchai Pruksapong, MD, FRCST Supat Chamnanchanunt, MD Vipa Thanachartwet, MD Varunee Desakorn, MPH, MSc Daochompu Nakawiro, MD Duangjai Sahassananda, MSc Ponlapat Rojnuckarin, MD, PhD Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study Plastic and Reconstructive Surgery, Global Open |
| title | Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study |
| title_full | Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study |
| title_fullStr | Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study |
| title_full_unstemmed | Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study |
| title_short | Association of Body Dysmorphic Disorder with Leptin Levels in Patients with Normal Weight Undergoing Liposuction: A Matched Case Study |
| title_sort | association of body dysmorphic disorder with leptin levels in patients with normal weight undergoing liposuction a matched case study |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002482 |
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