5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
The dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activi...
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Format: | Article |
Language: | English |
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Львівський національний університет імені Івана Франка
2009-12-01
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Series: | Біологічні студії |
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Online Access: | http://publications.lnu.edu.ua/journals/index.php/biology/article/view/487 |
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author | H. P. Kopylchuk I. M. Buchkovska O. M. Voloschuk |
author_facet | H. P. Kopylchuk I. M. Buchkovska O. M. Voloschuk |
author_sort | H. P. Kopylchuk |
collection | DOAJ |
description | The dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activities tumor-bearing rat in liver postnuclear fraction, reaching their maximal levels at the terminal stage of carcinogenesis. Similar dynamics of AMP-deaminase activity was observed in blood serum of animals under study. At the same time, 5′-nucleotidase activity reached its maximal level at the logarithmic stage and decreased at the stages of stationary growth and tumor metastasis. |
first_indexed | 2024-12-17T09:30:34Z |
format | Article |
id | doaj.art-e3d2508851034b0db047a9582d9169fe |
institution | Directory Open Access Journal |
issn | 1996-4536 2311-0783 |
language | English |
last_indexed | 2024-12-17T09:30:34Z |
publishDate | 2009-12-01 |
publisher | Львівський національний університет імені Івана Франка |
record_format | Article |
series | Біологічні студії |
spelling | doaj.art-e3d2508851034b0db047a9582d9169fe2022-12-21T21:54:15ZengЛьвівський національний університет імені Івана ФранкаБіологічні студії1996-45362311-07832009-12-0133697410.30970/sbi.0303.0345′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinomaH. P. Kopylchuk0https://orcid.org/0000-0002-2906-4927I. M. Buchkovska1https://orcid.org/0000-0002-9459-7295O. M. Voloschuk2Yuriy Fedkovych Chernivtsi National University, UkraineYuriy Fedkovych Chernivtsi National University, UkraineYuriy Fedkovych Chernivtsi National University, UkraineThe dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activities tumor-bearing rat in liver postnuclear fraction, reaching their maximal levels at the terminal stage of carcinogenesis. Similar dynamics of AMP-deaminase activity was observed in blood serum of animals under study. At the same time, 5′-nucleotidase activity reached its maximal level at the logarithmic stage and decreased at the stages of stationary growth and tumor metastasis.http://publications.lnu.edu.ua/journals/index.php/biology/article/view/4875′-nucleotidaseamp-deaminaseguerin’s carcinomaliverblood serumrats |
spellingShingle | H. P. Kopylchuk I. M. Buchkovska O. M. Voloschuk 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma Біологічні студії 5′-nucleotidase amp-deaminase guerin’s carcinoma liver blood serum rats |
title | 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma |
title_full | 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma |
title_fullStr | 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma |
title_full_unstemmed | 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma |
title_short | 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma |
title_sort | 5 nucleotidase and amp deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted guerin s carcinoma |
topic | 5′-nucleotidase amp-deaminase guerin’s carcinoma liver blood serum rats |
url | http://publications.lnu.edu.ua/journals/index.php/biology/article/view/487 |
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