5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma

The dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activi...

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Main Authors: H. P. Kopylchuk, I. M. Buchkovska, O. M. Voloschuk
Format: Article
Language:English
Published: Львівський національний університет імені Івана Франка 2009-12-01
Series:Біологічні студії
Subjects:
Online Access:http://publications.lnu.edu.ua/journals/index.php/biology/article/view/487
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author H. P. Kopylchuk
I. M. Buchkovska
O. M. Voloschuk
author_facet H. P. Kopylchuk
I. M. Buchkovska
O. M. Voloschuk
author_sort H. P. Kopylchuk
collection DOAJ
description The dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activities tumor-bearing rat in liver postnuclear fraction, reaching their maximal levels at the terminal stage of carcinogenesis. Similar dyna­mics of AMP-deaminase activity was observed in blood serum of animals under study. At the same time, 5′-nucleotidase activity reached its maximal level at the logarithmic stage and decreased at the stages of stationary growth and tumor metastasis.
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publisher Львівський національний університет імені Івана Франка
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spelling doaj.art-e3d2508851034b0db047a9582d9169fe2022-12-21T21:54:15ZengЛьвівський національний університет імені Івана ФранкаБіологічні студії1996-45362311-07832009-12-0133697410.30970/sbi.0303.0345′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinomaH. P. Kopylchuk0https://orcid.org/0000-0002-2906-4927I. M. Buchkovska1https://orcid.org/0000-0002-9459-7295O. M. Voloschuk2Yuriy Fedkovych Chernivtsi National University, UkraineYuriy Fedkovych Chernivtsi National University, UkraineYuriy Fedkovych Chernivtsi National University, UkraineThe dynamics of the levels of 5′-nucleotidase and AMP-deaminase activity in postnuclear fraction of rat liver and serum was studied during transplanted Guerin’s carcinoma growth in rats. It was found that the malignant growth is accompanied by the increase of 5′-nucleotidase and AMP-deaminase activities tumor-bearing rat in liver postnuclear fraction, reaching their maximal levels at the terminal stage of carcinogenesis. Similar dyna­mics of AMP-deaminase activity was observed in blood serum of animals under study. At the same time, 5′-nucleotidase activity reached its maximal level at the logarithmic stage and decreased at the stages of stationary growth and tumor metastasis.http://publications.lnu.edu.ua/journals/index.php/biology/article/view/4875′-nucleotidaseamp-deaminaseguerin’s carcinomaliverblood serumrats
spellingShingle H. P. Kopylchuk
I. M. Buchkovska
O. M. Voloschuk
5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
Біологічні студії
5′-nucleotidase
amp-deaminase
guerin’s carcinoma
liver
blood serum
rats
title 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
title_full 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
title_fullStr 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
title_full_unstemmed 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
title_short 5′-Nucleotidase and AMP-deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted Guerin’s carcinoma
title_sort 5 nucleotidase and amp deaminase activities of liver postnuclear fraction and blood serum of rats with transplanted guerin s carcinoma
topic 5′-nucleotidase
amp-deaminase
guerin’s carcinoma
liver
blood serum
rats
url http://publications.lnu.edu.ua/journals/index.php/biology/article/view/487
work_keys_str_mv AT hpkopylchuk 5nucleotidaseandampdeaminaseactivitiesofliverpostnuclearfractionandbloodserumofratswithtransplantedguerinscarcinoma
AT imbuchkovska 5nucleotidaseandampdeaminaseactivitiesofliverpostnuclearfractionandbloodserumofratswithtransplantedguerinscarcinoma
AT omvoloschuk 5nucleotidaseandampdeaminaseactivitiesofliverpostnuclearfractionandbloodserumofratswithtransplantedguerinscarcinoma