Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model

Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model

(1) Background: The psychoactive and non-psychoactive constituents of cannabis, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), synergistically reduce allodynia in various animal models of neuropathic pain. Unfortunately, THC-containing drugs also produce substantial side-effects when administe...

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Bibliographic Details
Main Authors: Sherelle L. Casey, Vanessa A. Mitchell, Eddy E. Sokolaj, Bryony L. Winters, Christopher W. Vaughan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
cannabinoid
neuropathic pain
THC
cannabidiol
synergy
intrathecal
Online Access:https://www.mdpi.com/1422-0067/23/15/8649

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