mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in <named-content content-type="genus-species">Candida albicans</named-content>
ABSTRACT J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how “Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity” (S. M. Noble, S. Frenc...
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2019-06-01
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| Series: | mSphere |
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| Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00258-19 |
| Summary: | ABSTRACT J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how “Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity” (S. M. Noble, S. French, L. A. Kohn, V. Chen, et al., Nat Genet 42:590–598, 2010, https://doi.org/10.1038/ng.605) provided tools and a blueprint for open-ended genetic screens in an organism that had been a challenge for genetic manipulation. |
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| ISSN: | 2379-5042 |