Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery
Background: Bariatric surgery is associated with significant risk reduction for obesity-related and hormone-mediated cancers; however, few studies report gastric or esophageal cancer development after bariatric surgery. This study evaluates the incidence of pre-cancerous mucosal lesions one year aft...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Advanced Biomedical Research |
| Subjects: | |
| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=140;epage=140;aulast=Keleidari |
| _version_ | 1797649535862833152 |
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| author | Behrooz Keleidari Hamid Melali Mohsen Mahmoudieh Dehkordi Masoud Sayadi Fatemeh Allahbakhshian Farsani Mohammad Fakhrolmobasheri Mahmood Mostafavi |
| author_facet | Behrooz Keleidari Hamid Melali Mohsen Mahmoudieh Dehkordi Masoud Sayadi Fatemeh Allahbakhshian Farsani Mohammad Fakhrolmobasheri Mahmood Mostafavi |
| author_sort | Behrooz Keleidari |
| collection | DOAJ |
| description | Background: Bariatric surgery is associated with significant risk reduction for obesity-related and hormone-mediated cancers; however, few studies report gastric or esophageal cancer development after bariatric surgery. This study evaluates the incidence of pre-cancerous mucosal lesions one year after bariatric surgery.
Materials and Methods: Eligible patients for omega-loop gastric bypass and classic Roux-en-Y gastric bypass (RYGB) underwent upper endoscopy before bariatric surgery and one year after the procedure. Several biopsies were obtained from esophagogastric mucosa, all of which were evaluated by pathologists regarding the development of any pre-cancerous lesion.
Results: A total of 108 patients were included in the study. Seventy-one underwent omega bypass and 37 classic RYGB. Follow-up endoscopy indicated no dysplastic changes in esophagogastric mucosa one year after the surgery. The number of patients with gastric intestinal metaplasia was 22 and 25 before and after the surgery, respectively, which was not a statistically significant increase.
Conclusion: Bariatric surgeries might not increase the risk of developing pre-cancerous lesions in the esophagogastric mucosa. Further epidemiological studies may help to establish this finding. |
| first_indexed | 2024-03-11T15:48:29Z |
| format | Article |
| id | doaj.art-e3dc2ae2ee5d4ec6bcc57792122403ef |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-03-11T15:48:29Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-e3dc2ae2ee5d4ec6bcc57792122403ef2023-10-26T05:43:17ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752023-01-0112114014010.4103/abr.abr_148_22Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgeryBehrooz KeleidariHamid MelaliMohsen Mahmoudieh DehkordiMasoud SayadiFatemeh Allahbakhshian FarsaniMohammad FakhrolmobasheriMahmood MostafaviBackground: Bariatric surgery is associated with significant risk reduction for obesity-related and hormone-mediated cancers; however, few studies report gastric or esophageal cancer development after bariatric surgery. This study evaluates the incidence of pre-cancerous mucosal lesions one year after bariatric surgery. Materials and Methods: Eligible patients for omega-loop gastric bypass and classic Roux-en-Y gastric bypass (RYGB) underwent upper endoscopy before bariatric surgery and one year after the procedure. Several biopsies were obtained from esophagogastric mucosa, all of which were evaluated by pathologists regarding the development of any pre-cancerous lesion. Results: A total of 108 patients were included in the study. Seventy-one underwent omega bypass and 37 classic RYGB. Follow-up endoscopy indicated no dysplastic changes in esophagogastric mucosa one year after the surgery. The number of patients with gastric intestinal metaplasia was 22 and 25 before and after the surgery, respectively, which was not a statistically significant increase. Conclusion: Bariatric surgeries might not increase the risk of developing pre-cancerous lesions in the esophagogastric mucosa. Further epidemiological studies may help to establish this finding.http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=140;epage=140;aulast=Keleidaribariatric surgeryobesitystomach neoplasms |
| spellingShingle | Behrooz Keleidari Hamid Melali Mohsen Mahmoudieh Dehkordi Masoud Sayadi Fatemeh Allahbakhshian Farsani Mohammad Fakhrolmobasheri Mahmood Mostafavi Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery Advanced Biomedical Research bariatric surgery obesity stomach neoplasms |
| title | Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery |
| title_full | Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery |
| title_fullStr | Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery |
| title_full_unstemmed | Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery |
| title_short | Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery |
| title_sort | evaluation of the incidence of the esophagogastric pre cancerous mucosal lesions after bariatric surgery |
| topic | bariatric surgery obesity stomach neoplasms |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=140;epage=140;aulast=Keleidari |
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