Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates
<p>Abstract</p> <p>Background</p> <p>About 45% of the human genome is comprised of mobile transposable elements or "junk DNA". The exaptation or co-option of these elements to provide important cellular functions is hypothesized to have played a powerful force...
Main Authors: | Koeffler H Phillip, Saito Tsuyako, Gombart Adrian F |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-07-01
|
Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/10/321 |
Similar Items
-
An evolutionary driver of interspersed segmental duplications in primates
by: Stuart Cantsilieris, et al.
Published: (2020-08-01) -
Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH
by: Manvendra Singh, et al.
Published: (2023-07-01) -
Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.
by: Andrea M Santangelo, et al.
Published: (2007-10-01) -
The exaptation of endocrine pharmacology
by: Sanjay Kalra, et al.
Published: (2012-01-01) -
Alu elements in primates are preferentially lost from areas of high GC content
by: Elizabeth HB Hellen, et al.
Published: (2013-05-01)