Numb is required for optimal contraction of skeletal muscle

Numb is required for optimal contraction of skeletal muscle

Abstract Background The role of Numb, a protein that is important for cell fate and development and that, in human muscle, is expressed at reduced levels with advanced age, was investigated; adult mice skeletal muscle and its localization and function within myofibres were determined. Methods Numb e...

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Bibliographic Details
Main Authors: Rita De Gasperi, Chenglin Mo, Daniella Azulai, Zhiying Wang, Lauren M. Harlow, Yating Du, Zachary Graham, Jiangping Pan, Xin‐hua Liu, Lei Guo, Bin Zhang, Fred Ko, Ashleigh M. Raczkowski, William A. Bauman, Chris N. Goulbourne, Wei Zhao, Marco Brotto, Christopher P. Cardozo
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Ageing
Sarcopenia
Excitation contraction coupling
Sarcomere
Mitochondria
Online Access:https://doi.org/10.1002/jcsm.12907

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