The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial
Strabismus surgery is associated with postoperative nausea-vomiting (PONV) and pain. In this prospective-randomized trial we aimed to investigate the effects of intra-operative paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children. Following approval...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Society of Turaz Bilim
2022-06-01
|
| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=127771 |
| _version_ | 1797328139623333888 |
|---|---|
| author | Hulya Gundogdu Zeliha Korkmaz Disli Nalan Ornek Celebi |
| author_facet | Hulya Gundogdu Zeliha Korkmaz Disli Nalan Ornek Celebi |
| author_sort | Hulya Gundogdu |
| collection | DOAJ |
| description | Strabismus surgery is associated with postoperative nausea-vomiting (PONV) and pain. In this prospective-randomized trial we aimed to investigate the effects of intra-operative paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children. Following approval of ethical committee 50 pediatric patients aged between 3-12 physical status of ASA I-II (American Society of Anesthesiology) undergoing strabismus surgery are included in the study between 2012 and 2013 years. Patients were excluded from the study for these following reasons: known allergic history to paracetamol or other non-steroidal anti-inflammatory drugs (NSAID), morphine and other drugs used in the study; asthma; liver or kidney dysfunction and bleeding disorders. Patients were randomized into two following groups: intravenous paracetamol and IV morphine. Demographic data were similar among groups. Nausea, vomiting scales and anti-emetic requirement of the groups were compared at 0.min, 30.min, 2 hrs and 24 hrs. Analysis had shown that there is a significant difference at the 30th minute, there were no significant differences at other time periods. Wong-Baker faces pain rating scale were compared between groups at 0.min, 30.min, 2 hrs and 24 hrs and no significant differences were seen between group (p > 0.05). Analgesic requirement and sedation scores were compared between groups at 0 min, 30 min, 2 hrs and 24 hrs and no significant differences were seen between groups (p < 0.05). It can be concluded that intravenous paracetamol infusion can safely be used as a replacement to opioids in children undergoing strabismus surgery. [Med-Science 2022; 11(2.000): 496-501] |
| first_indexed | 2024-03-08T06:47:39Z |
| format | Article |
| id | doaj.art-e3e14bd3a46340c39f8b70a319b1d38f |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T06:47:39Z |
| publishDate | 2022-06-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-e3e14bd3a46340c39f8b70a319b1d38f2024-02-03T07:29:11ZengSociety of Turaz BilimMedicine Science2147-06342022-06-0111249650110.5455/medscience.2021.09.317127771The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trialHulya Gundogdu0Zeliha Korkmaz DisliNalan Ornek CelebiAnkara City Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey Inonu University, Turgut Ozal Medicine Center, Department of Anesthesiology and Reanimation, Ankara, Turkey Hacettepe University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Ankara, TurkeyStrabismus surgery is associated with postoperative nausea-vomiting (PONV) and pain. In this prospective-randomized trial we aimed to investigate the effects of intra-operative paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children. Following approval of ethical committee 50 pediatric patients aged between 3-12 physical status of ASA I-II (American Society of Anesthesiology) undergoing strabismus surgery are included in the study between 2012 and 2013 years. Patients were excluded from the study for these following reasons: known allergic history to paracetamol or other non-steroidal anti-inflammatory drugs (NSAID), morphine and other drugs used in the study; asthma; liver or kidney dysfunction and bleeding disorders. Patients were randomized into two following groups: intravenous paracetamol and IV morphine. Demographic data were similar among groups. Nausea, vomiting scales and anti-emetic requirement of the groups were compared at 0.min, 30.min, 2 hrs and 24 hrs. Analysis had shown that there is a significant difference at the 30th minute, there were no significant differences at other time periods. Wong-Baker faces pain rating scale were compared between groups at 0.min, 30.min, 2 hrs and 24 hrs and no significant differences were seen between group (p > 0.05). Analgesic requirement and sedation scores were compared between groups at 0 min, 30 min, 2 hrs and 24 hrs and no significant differences were seen between groups (p < 0.05). It can be concluded that intravenous paracetamol infusion can safely be used as a replacement to opioids in children undergoing strabismus surgery. [Med-Science 2022; 11(2.000): 496-501]http://www.ejmanager.com/fulltextpdf.php?mno=127771morphineparacetamolpostoperative nausea-vomitingpain scalestrabismus surgery |
| spellingShingle | Hulya Gundogdu Zeliha Korkmaz Disli Nalan Ornek Celebi The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial Medicine Science morphine paracetamol postoperative nausea-vomiting pain scale strabismus surgery |
| title | The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial |
| title_full | The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial |
| title_fullStr | The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial |
| title_full_unstemmed | The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial |
| title_short | The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial |
| title_sort | effect of intravenous paracetamol infusion on postoperative nausea vomiting and pain following strabismus surgery in children a randomised controlled trial |
| topic | morphine paracetamol postoperative nausea-vomiting pain scale strabismus surgery |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=127771 |
| work_keys_str_mv | AT hulyagundogdu theeffectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial AT zelihakorkmazdisli theeffectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial AT nalanornekcelebi theeffectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial AT hulyagundogdu effectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial AT zelihakorkmazdisli effectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial AT nalanornekcelebi effectofintravenousparacetamolinfusiononpostoperativenauseavomitingandpainfollowingstrabismussurgeryinchildrenarandomisedcontrolledtrial |