Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche
Stem cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with the production of daughters that leave the niche to differentiate. We discovered a mechanism of stem cell niche exit in the canonical C. elegans distal tip cell (DTC) germ stem cell niche mediated...
Main Authors: | Kacy L Gordon, Jay W Zussman, Xin Li, Camille Miller, David R Sherwood |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/56383 |
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