The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19
Abstract Background Despite the confirmed association between higher BMI with increased risk of the acute respiratory distress syndrome (ARDS), the association between obesity with mortality in critically ill patients with coronavirus disease 2019 (COVID‐19) is not clear. The present study aimed to...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-11-01
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| Series: | Endocrinology, Diabetes & Metabolism |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/edm2.458 |
| _version_ | 1827765075130187776 |
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| author | Maryam Gholamalizadeh Mohammad Attari Mahdi Mousavi Soheila Shekari Zahra Salimi Asma Rajabi Harsini Mobina Zeinolabedin Amin Barzkar Zahra Mahmoudi Farkhondeh Alami Samaneh Mirzaei Dahka Somayeh Gholami Masoume Rahvar Masoume Pourtaleb Sara Khoshdooz Naser Kalantari Saeid Doaei |
| author_facet | Maryam Gholamalizadeh Mohammad Attari Mahdi Mousavi Soheila Shekari Zahra Salimi Asma Rajabi Harsini Mobina Zeinolabedin Amin Barzkar Zahra Mahmoudi Farkhondeh Alami Samaneh Mirzaei Dahka Somayeh Gholami Masoume Rahvar Masoume Pourtaleb Sara Khoshdooz Naser Kalantari Saeid Doaei |
| author_sort | Maryam Gholamalizadeh |
| collection | DOAJ |
| description | Abstract Background Despite the confirmed association between higher BMI with increased risk of the acute respiratory distress syndrome (ARDS), the association between obesity with mortality in critically ill patients with coronavirus disease 2019 (COVID‐19) is not clear. The present study aimed to investigate the association between obesity with treatment duration, ICU length of stay, and the risk of death in critically ill patients with COVID‐19. Methods This case–control study was performed on 223 patients with COVID‐19 including 148 surviving patients as the control group and 75 eventually dead patients as the case group in Rasht, Iran. Data on demographic factors, comorbidities, anthropometric measurements, the length of hospitalization and the mortality were obtained from patients' medical records. Results The mortality rate was significantly associated with weight (OR = 1.04, 95% CI: 1.002–1.083, p = .04), but not with BMI after adjustments for age, gender, length of stay in ICU, chronic diseases and smoking. The results did not change after further adjustments for biochemical and pathological factors. Conclusions Weight was positively associated with mortality after controlling for confounding variables. Further studies should consider the patient's body composition such as fat mass to establish the relationship between obesity and COVID‐19 outcomes. |
| first_indexed | 2024-03-11T11:13:55Z |
| format | Article |
| id | doaj.art-e3e4820c361145f9952ee003b8dd806b |
| institution | Directory Open Access Journal |
| issn | 2398-9238 |
| language | English |
| last_indexed | 2024-03-11T11:13:55Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism |
| spelling | doaj.art-e3e4820c361145f9952ee003b8dd806b2023-11-11T09:37:05ZengWileyEndocrinology, Diabetes & Metabolism2398-92382023-11-0166n/an/a10.1002/edm2.458The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19Maryam Gholamalizadeh0Mohammad Attari1Mahdi Mousavi2Soheila Shekari3Zahra Salimi4Asma Rajabi Harsini5Mobina Zeinolabedin6Amin Barzkar7Zahra Mahmoudi8Farkhondeh Alami9Samaneh Mirzaei Dahka10Somayeh Gholami11Masoume Rahvar12Masoume Pourtaleb13Sara Khoshdooz14Naser Kalantari15Saeid Doaei16Student Research Committee, Cancer Research Center Shahid Beheshti University of Medical Sciences Tehran IranLoghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran IranStudent Research Center Tabriz University of Medical Sciences Tabriz IranDepartment of Nutrition, Science and Research Branch Islamic Azad University Tehran IranNutrition and Metabolic Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz IranDepartment of Clinical Nutrition School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS) Tehran IranDepartment of Community Nutrition School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS) Tehran IranKerman University of Medical Sciences Kerman IranDepartment of Nutrition, Science and Research Branch Islamic Azad University Tehran IranStudent Research Committee, Department of Nutrition, Faculty of Medicine Urmia University of Medical Sciences Urmia IranSchool of Nursing and Midwifery Guilan University of Medical Sciences Rasht IranIntensive Care Unit (ICU) Razi Hospital, Guilan University of Medical Sciences Rasht IranSchool of Health Guilan University of Medical Sciences Rasht IranSchool of Health Guilan University of Medical Sciences Rasht IranFaculty of Medicine Guilan University of Medical Science Rasht IranDepartment of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences Tehran IranDepartment of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences Tehran IranAbstract Background Despite the confirmed association between higher BMI with increased risk of the acute respiratory distress syndrome (ARDS), the association between obesity with mortality in critically ill patients with coronavirus disease 2019 (COVID‐19) is not clear. The present study aimed to investigate the association between obesity with treatment duration, ICU length of stay, and the risk of death in critically ill patients with COVID‐19. Methods This case–control study was performed on 223 patients with COVID‐19 including 148 surviving patients as the control group and 75 eventually dead patients as the case group in Rasht, Iran. Data on demographic factors, comorbidities, anthropometric measurements, the length of hospitalization and the mortality were obtained from patients' medical records. Results The mortality rate was significantly associated with weight (OR = 1.04, 95% CI: 1.002–1.083, p = .04), but not with BMI after adjustments for age, gender, length of stay in ICU, chronic diseases and smoking. The results did not change after further adjustments for biochemical and pathological factors. Conclusions Weight was positively associated with mortality after controlling for confounding variables. Further studies should consider the patient's body composition such as fat mass to establish the relationship between obesity and COVID‐19 outcomes.https://doi.org/10.1002/edm2.458bodyweightCOVID‐19ICUmortalityobesity |
| spellingShingle | Maryam Gholamalizadeh Mohammad Attari Mahdi Mousavi Soheila Shekari Zahra Salimi Asma Rajabi Harsini Mobina Zeinolabedin Amin Barzkar Zahra Mahmoudi Farkhondeh Alami Samaneh Mirzaei Dahka Somayeh Gholami Masoume Rahvar Masoume Pourtaleb Sara Khoshdooz Naser Kalantari Saeid Doaei The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 Endocrinology, Diabetes & Metabolism bodyweight COVID‐19 ICU mortality obesity |
| title | The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 |
| title_full | The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 |
| title_fullStr | The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 |
| title_full_unstemmed | The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 |
| title_short | The association between obesity with treatment duration, ICU length of stay and the risk of death in critically ill patients with COVID‐19 |
| title_sort | association between obesity with treatment duration icu length of stay and the risk of death in critically ill patients with covid 19 |
| topic | bodyweight COVID‐19 ICU mortality obesity |
| url | https://doi.org/10.1002/edm2.458 |
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