Research progress in the effectiveness and mechanism of hyperbaric oxygen therapy for depression

Hyperbaric oxygen therapy characterized by fewer side effects and simple operation has been explored as a potential therapy for depression. This article provides a review of researches relevant to current clinical application and mechanism of hyperbaric oxygen therapy for depression, aiming to provi...

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Bibliographic Details
Main Authors: Xiao Lin, Zhang Xiaomei, Wu Kai, Wang Lu
Format: Article
Language:zho
Published: Editorial Office of Sichuan Mental Health 2024-02-01
Series:Sichuan jingshen weisheng
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Online Access:http://www.psychjm.net.cn/scjswszzen/ch/reader/view_abstract.aspx?file_no=202401017&flag=1
Description
Summary:Hyperbaric oxygen therapy characterized by fewer side effects and simple operation has been explored as a potential therapy for depression. This article provides a review of researches relevant to current clinical application and mechanism of hyperbaric oxygen therapy for depression, aiming to provide valuable references for the formulation of new strategies for the treatment of depression. Hyperbaric oxygen therapy has been demonstrated to be useful as an adjunctive therapy for depression, which can effectively alleviate depression by regulating the homeostasis of hypothalamus-pituitary-adrenal axis, inhibiting inflammation and enhancing synaptic plasticity. And hyperbaric oxygen therapy as adjuvant to antidepressants for depression can contribute to increasing the treatment effectiveness to some extent.
ISSN:1007-3256