Endothelial Cell Plasma Membrane Biomechanics Mediates Effects of Pro-Inflammatory Factors on Endothelial Mechanosensors: Vicious Circle Formation in Atherogenic Inflammation

Endothelial Cell Plasma Membrane Biomechanics Mediates Effects of Pro-Inflammatory Factors on Endothelial Mechanosensors: Vicious Circle Formation in Atherogenic Inflammation

Chronic low-grade vascular inflammation and endothelial dysfunction significantly contribute to the pathogenesis of cardiovascular diseases. In endothelial cells (ECs), anti-inflammatory or pro-inflammatory signaling can be induced by different patterns of the fluid shear stress (SS) exerted by bloo...

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Bibliographic Details
Main Authors: Nadezhda Barvitenko, Mohammad Ashrafuzzaman, Alfons Lawen, Elisaveta Skverchinskaya, Carlota Saldanha, Alessia Manca, Giuseppe Uras, Muhammad Aslam, Antonella Pantaleo
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
shear stress
inflammation
endothelial cell
lipid bilayer
cytoskeleton
mechanosensor
Online Access:https://www.mdpi.com/2077-0375/12/2/205

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