Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings

Suicide affects all sociodemographic levels, age groups, and populations worldwide. The factors that can increase the risk of suicidal tendencies are widely studied. The aim of this study was to analyze the types and combinations of toxics found in fatal suicide victims with different suicide mechan...

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Main Authors: Aurelia Collados-Ros, Carmen Torres-Sánchez, María Dolores Pérez-Cárceles, Aurelio Luna, Isabel Legaz
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/10/6/319
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author Aurelia Collados-Ros
Carmen Torres-Sánchez
María Dolores Pérez-Cárceles
Aurelio Luna
Isabel Legaz
author_facet Aurelia Collados-Ros
Carmen Torres-Sánchez
María Dolores Pérez-Cárceles
Aurelio Luna
Isabel Legaz
author_sort Aurelia Collados-Ros
collection DOAJ
description Suicide affects all sociodemographic levels, age groups, and populations worldwide. The factors that can increase the risk of suicidal tendencies are widely studied. The aim of this study was to analyze the types and combinations of toxics found in fatal suicide victims with different suicide mechanisms. A total of 355 autopsies were retrospectively studied, and 26 toxics were determined and related to mechanisms of suicide. Hanging (55%), drug overdose (22.7%), and jumping from a height (17.8%) were most represented suicide mechanisms with positive toxicology. Hanging was the most represented in men (50.3%; <i>p</i> = 0.019), while jumping from a height was more represented in women (29.7%, <i>p</i> = 0.028). Drugs of abuse were the most frequent toxics found in men (55.5%; <i>p</i> < 0.001), while medicines were the most frequent type found in women (70.3%, <i>p</i> < 0.001). Alcohol, nordiazepam, cocaine, and venlafaxine were the most consumed toxics. Benzodiazepines and venlafaxine were found in suicides involving drug overdose, hanging, and jumping from a height. In conclusion, most suicides were associated with drug abuse in men. Hanging was more represented in men and jumping from a height in women. Alcohol was present in combination with other toxics and medicines. The toxicological analysis is fundamental to understanding consumption patterns and establishing strategies and protocols for detecting and preventing suicide.
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spelling doaj.art-e3ea53631034411d8a4a9894216b14802023-11-23T19:16:16ZengMDPI AGToxics2305-63042022-06-0110631910.3390/toxics10060319Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological FindingsAurelia Collados-Ros0Carmen Torres-Sánchez1María Dolores Pérez-Cárceles2Aurelio Luna3Isabel Legaz4Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, SpainDepartment of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, SpainDepartment of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, SpainDepartment of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, SpainDepartment of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, SpainSuicide affects all sociodemographic levels, age groups, and populations worldwide. The factors that can increase the risk of suicidal tendencies are widely studied. The aim of this study was to analyze the types and combinations of toxics found in fatal suicide victims with different suicide mechanisms. A total of 355 autopsies were retrospectively studied, and 26 toxics were determined and related to mechanisms of suicide. Hanging (55%), drug overdose (22.7%), and jumping from a height (17.8%) were most represented suicide mechanisms with positive toxicology. Hanging was the most represented in men (50.3%; <i>p</i> = 0.019), while jumping from a height was more represented in women (29.7%, <i>p</i> = 0.028). Drugs of abuse were the most frequent toxics found in men (55.5%; <i>p</i> < 0.001), while medicines were the most frequent type found in women (70.3%, <i>p</i> < 0.001). Alcohol, nordiazepam, cocaine, and venlafaxine were the most consumed toxics. Benzodiazepines and venlafaxine were found in suicides involving drug overdose, hanging, and jumping from a height. In conclusion, most suicides were associated with drug abuse in men. Hanging was more represented in men and jumping from a height in women. Alcohol was present in combination with other toxics and medicines. The toxicological analysis is fundamental to understanding consumption patterns and establishing strategies and protocols for detecting and preventing suicide.https://www.mdpi.com/2305-6304/10/6/319alcoholautopsiesdrugs of abuseforensic toxicologypsychotropic drugssuicides
spellingShingle Aurelia Collados-Ros
Carmen Torres-Sánchez
María Dolores Pérez-Cárceles
Aurelio Luna
Isabel Legaz
Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
Toxics
alcohol
autopsies
drugs of abuse
forensic toxicology
psychotropic drugs
suicides
title Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
title_full Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
title_fullStr Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
title_full_unstemmed Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
title_short Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings
title_sort suicidal behavior and its relationship with postmortem forensic toxicological findings
topic alcohol
autopsies
drugs of abuse
forensic toxicology
psychotropic drugs
suicides
url https://www.mdpi.com/2305-6304/10/6/319
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AT aurelioluna suicidalbehavioranditsrelationshipwithpostmortemforensictoxicologicalfindings
AT isabellegaz suicidalbehavioranditsrelationshipwithpostmortemforensictoxicologicalfindings