Psychiatric comorbidity profiles among suicidal attempters: A cohort study

Introduction More than 700,000 people die by suicide in 2019 globally (World Health Organitation 2021). Mental health problems constitute a risk factor for suicidal behavior and death by suicide (Hoertel et al. Mol Psychiatry 2015; 20 718–726). Different mental disorders have been related to differ...

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Main Authors: Y. Sanchez-Carro, M. Diaz-Marsa, V. Fernandez-Rodrigues, W. Ayad-Ahmed, A. Pemau, I. Perez-Diaz, A. Galvez-Merlin, P. de la Higuera-Gonzalez, V. Perez-Sola, P. Saiz, I. Grande, A. Cebria, J. Andreo-Jover, P. Lopez-Peña, M. Ruiz-Veguilla, A. de la Torre-Luque
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823007058/type/journal_article
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author Y. Sanchez-Carro
M. Diaz-Marsa
V. Fernandez-Rodrigues
W. Ayad-Ahmed
A. Pemau
I. Perez-Diaz
A. Galvez-Merlin
P. de la Higuera-Gonzalez
V. Perez-Sola
P. Saiz
I. Grande
A. Cebria
J. Andreo-Jover
P. Lopez-Peña
M. Ruiz-Veguilla
A. de la Torre-Luque
author_facet Y. Sanchez-Carro
M. Diaz-Marsa
V. Fernandez-Rodrigues
W. Ayad-Ahmed
A. Pemau
I. Perez-Diaz
A. Galvez-Merlin
P. de la Higuera-Gonzalez
V. Perez-Sola
P. Saiz
I. Grande
A. Cebria
J. Andreo-Jover
P. Lopez-Peña
M. Ruiz-Veguilla
A. de la Torre-Luque
author_sort Y. Sanchez-Carro
collection DOAJ
description Introduction More than 700,000 people die by suicide in 2019 globally (World Health Organitation 2021). Mental health problems constitute a risk factor for suicidal behavior and death by suicide (Hoertel et al. Mol Psychiatry 2015; 20 718–726). Different mental disorders have been related to different forms of suicidal ideation and behavior (Conejero et al. Curr Psychiatry Rep 2018; 20, 33) (Quevedo et al. Compr Psychiatry 2020; 102 152194). However, little is known on comorbidity profiles among suicide attempters. Objectives The aim of our work was to identify the psychiatric comorbidity profiles of individuals who were admitted a hospital emergency department due to a suicide attempt. Moreover, it intended to know their clinical characteristics according to comorbidity profile. Methods A sample of 683 attempters (71.30% female; M age= 40.85, SD= 15.48) from the SURVIVE study was used. Patients were assessed within the 15 days after emergency department admission. Sociodemographic (i.e., sex, age, marital status and employment status) and clinical data were collected. The International Neuropsychiatric Interview (MINI) was used to assess DSM-V Axis 1 mental health diagnoses and the Columbia Suicide Rating Scale (C-SSRS) to assess suicidal ideation and behavior. The Acquired Capacity for Suicide-Fear of Death Scale (ACSS-FAD), the Patient Health Questionnaire (PHQ-9) to assess the frequency of depressive symptoms during the past 2 weeks, and the General Anxiety Disorder-7 (GAD-7) scale to assess symptoms of worry and anxiety were also conducted. For the identification of comorbidity profiles, latent class analysis framework was followed considering diagnosis to each individual disorder as clustering variables. On the other hand, binary logistic regression was used to study the relationship between comorbidity profile membership and clinical factors. Results Two classes were found (Class I= mild symptomatology class, mainly featured by emotional disorder endorsement; and Class II= high comorbidity class, featured by a wide amount of endorsed diagnoses) (see figure 1). Individuals from the High comorbidity class were more likely to be female (OR= 0.98, p<.05), younger in age (OR= 0.52, p< .01), with more depressive symptoms (OR=1.09, p<.001) and have greater impulsivity (OR= 1.01, p<.05). Image: Conclusions We found two profiles of people with suicidal behavior based on the presence of mental disorders. Each of the suicidal subtypes had different associated risk factors. They also had a different profile of suicidal behavior. Disclosure of Interest None Declared
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spelling doaj.art-e3ec4c04dc594f8b9a03ab1eaf525a942023-11-17T05:08:04ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S318S31910.1192/j.eurpsy.2023.705Psychiatric comorbidity profiles among suicidal attempters: A cohort studyY. Sanchez-Carro0M. Diaz-Marsa1V. Fernandez-Rodrigues2W. Ayad-Ahmed3A. Pemau4I. Perez-Diaz5A. Galvez-Merlin6P. de la Higuera-Gonzalez7V. Perez-Sola8P. Saiz9I. Grande10A. Cebria11J. Andreo-Jover12P. Lopez-Peña13M. Ruiz-Veguilla14A. de la Torre-Luque151Universidad Autonoma de Madrid 2Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII)3CIBERSAM ISCIII 4Universidad Complutense de Madrid 5Health Research Institute, Hospital Clínico San Carlos (IdISSC)5Health Research Institute, Hospital Clínico San Carlos (IdISSC) 6Department of Personality, Assessment and Clinical Psychology, Faculty of Psychology5Health Research Institute, Hospital Clínico San Carlos (IdISSC)6Department of Personality, Assessment and Clinical Psychology, Faculty of Psychology1Universidad Autonoma de Madrid7Department of Legal Medicine, Psychiatry and Pathology, Faculty of Medicine, Universidad Complutense de Madrid 8Health Research Institute, Hospital Clínico San Carlos (IdISSC)5Health Research Institute, Hospital Clínico San Carlos (IdISSC) 6Department of Personality, Assessment and Clinical Psychology, Faculty of Psychology9Institut Hospital del Mar d’Investigacions Mediques (IMIM) 10Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII), Madrid, Spain2Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII) 11Universidad de Oviedo, Oviedo12Bipolar and Depressive Disorders Unit, Hospital Clinic 13Institute of Neurosciences, University of Barcelona 14August Pi i Sunyer Biomedical Research Institute (IDIBAPS) 15Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII), Barcelona16Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII) 17Corporacio Sanitaria Parc Tauli, Sabadell1Universidad Autonoma de Madrid 18Instituto de Investigación del Hospital Universitario La Paz (IdiPAZ), Madrid2Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII) 18Instituto de Investigación del Hospital Universitario La Paz (IdiPAZ), Madrid19Hospital Universitario Virgen del Rocio 20Biomedical Research Networking Consortium for Mental Health (CIBERSAM ISCIII), Sevilla7Department of Legal Medicine, Psychiatry and Pathology, Faculty of Medicine, Universidad Complutense de Madrid 21Biomedical Research Networking Consortium for Mental Health (CIBERSAM), Madrid, Spain Introduction More than 700,000 people die by suicide in 2019 globally (World Health Organitation 2021). Mental health problems constitute a risk factor for suicidal behavior and death by suicide (Hoertel et al. Mol Psychiatry 2015; 20 718–726). Different mental disorders have been related to different forms of suicidal ideation and behavior (Conejero et al. Curr Psychiatry Rep 2018; 20, 33) (Quevedo et al. Compr Psychiatry 2020; 102 152194). However, little is known on comorbidity profiles among suicide attempters. Objectives The aim of our work was to identify the psychiatric comorbidity profiles of individuals who were admitted a hospital emergency department due to a suicide attempt. Moreover, it intended to know their clinical characteristics according to comorbidity profile. Methods A sample of 683 attempters (71.30% female; M age= 40.85, SD= 15.48) from the SURVIVE study was used. Patients were assessed within the 15 days after emergency department admission. Sociodemographic (i.e., sex, age, marital status and employment status) and clinical data were collected. The International Neuropsychiatric Interview (MINI) was used to assess DSM-V Axis 1 mental health diagnoses and the Columbia Suicide Rating Scale (C-SSRS) to assess suicidal ideation and behavior. The Acquired Capacity for Suicide-Fear of Death Scale (ACSS-FAD), the Patient Health Questionnaire (PHQ-9) to assess the frequency of depressive symptoms during the past 2 weeks, and the General Anxiety Disorder-7 (GAD-7) scale to assess symptoms of worry and anxiety were also conducted. For the identification of comorbidity profiles, latent class analysis framework was followed considering diagnosis to each individual disorder as clustering variables. On the other hand, binary logistic regression was used to study the relationship between comorbidity profile membership and clinical factors. Results Two classes were found (Class I= mild symptomatology class, mainly featured by emotional disorder endorsement; and Class II= high comorbidity class, featured by a wide amount of endorsed diagnoses) (see figure 1). Individuals from the High comorbidity class were more likely to be female (OR= 0.98, p<.05), younger in age (OR= 0.52, p< .01), with more depressive symptoms (OR=1.09, p<.001) and have greater impulsivity (OR= 1.01, p<.05). Image: Conclusions We found two profiles of people with suicidal behavior based on the presence of mental disorders. Each of the suicidal subtypes had different associated risk factors. They also had a different profile of suicidal behavior. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823007058/type/journal_article
spellingShingle Y. Sanchez-Carro
M. Diaz-Marsa
V. Fernandez-Rodrigues
W. Ayad-Ahmed
A. Pemau
I. Perez-Diaz
A. Galvez-Merlin
P. de la Higuera-Gonzalez
V. Perez-Sola
P. Saiz
I. Grande
A. Cebria
J. Andreo-Jover
P. Lopez-Peña
M. Ruiz-Veguilla
A. de la Torre-Luque
Psychiatric comorbidity profiles among suicidal attempters: A cohort study
European Psychiatry
title Psychiatric comorbidity profiles among suicidal attempters: A cohort study
title_full Psychiatric comorbidity profiles among suicidal attempters: A cohort study
title_fullStr Psychiatric comorbidity profiles among suicidal attempters: A cohort study
title_full_unstemmed Psychiatric comorbidity profiles among suicidal attempters: A cohort study
title_short Psychiatric comorbidity profiles among suicidal attempters: A cohort study
title_sort psychiatric comorbidity profiles among suicidal attempters a cohort study
url https://www.cambridge.org/core/product/identifier/S0924933823007058/type/journal_article
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